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Health-Related Quality of Life (HRQoL) Outcomes Following Injury in Childhood and Adolescence Using EuroQol (EQ-5D) Responses with Pooled Longitudinal Data

Author

Listed:
  • Joanna F. Dipnall

    (School of Public Health and Preventive Medicine, Monash University, Melbourne 3004, Australia
    Institute for Mental and Physical Health and Clinical Translation, School of Medicine, Deakin University, Geelong 3220, Australia)

  • Frederick P. Rivara

    (Departments of Pediatrics and Epidemiology, Harborview Injury Prevention and Research Center, University of Washington, Seattle, WA 98195, USA)

  • Ronan A. Lyons

    (School of Public Health and Preventive Medicine, Monash University, Melbourne 3004, Australia
    Health Data Research UK, Swansea University, Swansea SA2 8PP, UK
    National Centre for Population Health and Wellbeing Research, Swansea University, Swansea SA2 8PP, UK)

  • Shanthi Ameratunga

    (School of Public Health and Preventive Medicine, Monash University, Melbourne 3004, Australia
    School of Population Health, University of Auckland, Auckland 1023, New Zealand
    Kidz First Hospital and Population Health Directorate, Counties Manukau District Health Board, Auckland 2025, New Zealand)

  • Mariana Brussoni

    (Department of Pediatrics, School of Population and Public Health, University of British Columbia, Vancouver, BC V6H 3V4, Canada
    British Columbia Injury Research and Prevention Unit, British Columbia Children’s Hospital Research Institute, Vancouver, BC V6H 3V4, Canada
    Human Early Learning Partnership, School of Population and Public Health, University of British Columbia, Vancouver, BC V6T 1Z3, Canada)

  • Fiona E. Lecky

    (Centre for Urgent and Emergency Care Research, School of Health and Related Research, University of Sheffield, Sheffield S10 2TN, UK
    Emergency Department, Salford Royal Hospital, Salford M6 8HD, UK)

  • Clare Bradley

    (South Australian Health and Medical Research Institute, Adelaide 5001, Australia
    College of Medicine and Public Health, Flinders University, Bedford Park 5042, Australia)

  • Ben Beck

    (School of Public Health and Preventive Medicine, Monash University, Melbourne 3004, Australia)

  • Jane Lyons

    (Health Data Research UK, Swansea University, Swansea SA2 8PP, UK)

  • Amy Schneeberg

    (British Columbia Injury Research and Prevention Unit, British Columbia Children’s Hospital Research Institute, Vancouver, BC V6H 3V4, Canada
    School of Population and Public Health, University of British Columbia, Vancouver, BC V6T 1Z3, Canada)

  • James E. Harrison

    (College of Medicine and Public Health, Flinders University, Bedford Park 5042, Australia)

  • Belinda J. Gabbe

    (School of Public Health and Preventive Medicine, Monash University, Melbourne 3004, Australia
    Health Data Research UK, Swansea University, Swansea SA2 8PP, UK)

Abstract

Background: Injury is a leading contributor to the global disease burden in children, affecting their health-related quality of life (HRQoL)—yet valid estimates of burden are absent. Methods: This study pooled longitudinal data from five cohort studies of pediatric injury survivors (5–17 years) at baseline, 1-, 4-, 6-, 12-, and 24- months ( n = 2334). HRQoL post-injury was measured using the 3-level EQ-5D utility score (EQ-5D) and five health states (mobility, self-care, activity, pain, anxiety and depression (anxiety)). Results: Mean EQ-5D post-injury did not return to baseline level (0.95) by 24 months (0.88) and was lower for females over time (−0.04, 95%CI −0.05, −0.02). A decreased adjusted risk ratio over time (ARR) was observed for intentional injuries (pain: 0.85, 95%CI 0.73,0.98; anxiety: 0.62, 95%CI 0.49,0.78); spinal cord injuries (mobility: 0.61, 95%CI 0.45,0.83), self-care: 0.76, 95%CI 0.63,0.91, activity: 0.64, 95%CI 0.47,0.88); moderate/severe traumatic brain injury (activity: 0.83, 95%CI 0.71,0.96). ARRs were also low for certain fractures, with various health states affected. Conclusions: HRQoL outcomes over time for children and adolescents post-injury differed across key demographic and injury related attributes. HRQoL did not reach levels consistent with full health by 24 months with recovery plateauing from 6 to 24 months. Tailored interventions are required to respond to the varying post-injury recovery trajectories in this population.

Suggested Citation

  • Joanna F. Dipnall & Frederick P. Rivara & Ronan A. Lyons & Shanthi Ameratunga & Mariana Brussoni & Fiona E. Lecky & Clare Bradley & Ben Beck & Jane Lyons & Amy Schneeberg & James E. Harrison & Belinda, 2021. "Health-Related Quality of Life (HRQoL) Outcomes Following Injury in Childhood and Adolescence Using EuroQol (EQ-5D) Responses with Pooled Longitudinal Data," IJERPH, MDPI, vol. 18(19), pages 1-19, September.
    • Handle: RePEc:gam:jijerp:v:18:y:2021:i:19:p:10156-:d:644492
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    References listed on IDEAS

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    1. Kamran Khan & Stavros Petrou & Oliver Rivero-Arias & Stephen Walters & Spencer Boyle, 2014. "Mapping EQ-5D Utility Scores from the PedsQL™ Generic Core Scales," PharmacoEconomics, Springer, vol. 32(7), pages 693-706, July.
    2. Simone Weyers & Nico Dragano & Susanne Möbus & Eva-Maria Beck & Andreas Stang & Stephan Möhlenkamp & Karl Jöckel & Raimund Erbel & Johannes Siegrist, 2010. "Poor social relations and adverse health behaviour: stronger associations in low socioeconomic groups?," International Journal of Public Health, Springer;Swiss School of Public Health (SSPH+), vol. 55(1), pages 17-23, February.
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