IDEAS home Printed from https://ideas.repec.org/a/gam/jijerp/v17y2020i11p4041-d367949.html
   My bibliography  Save this article

Quality of Life and Symptom Burden among Chronic Kidney Disease of Uncertain Etiology (CKDu) Patients in Girandurukotte, Sri Lanka

Author

Listed:
  • Hansani Madushika Abeywickrama

    (Graduate School of Health Sciences, School of Health Sciences, Faculty of Medicine, Niigata University, 2-746, Asahimachi, Niigata 951-8518, Japan)

  • Swarna Wimalasiri

    (Department of Food Science and Technology, Faculty of Agriculture, University of Peradeniya, Kandy 20400, Sri Lanka)

  • Yu Koyama

    (Graduate School of Health Sciences, School of Health Sciences, Faculty of Medicine, Niigata University, 2-746, Asahimachi, Niigata 951-8518, Japan)

  • Mieko Uchiyama

    (Graduate School of Health Sciences, School of Health Sciences, Faculty of Medicine, Niigata University, 2-746, Asahimachi, Niigata 951-8518, Japan)

  • Utako Shimizu

    (Graduate School of Health Sciences, School of Health Sciences, Faculty of Medicine, Niigata University, 2-746, Asahimachi, Niigata 951-8518, Japan)

  • Nahoko Kakihara

    (Graduate School of Health Sciences, School of Health Sciences, Faculty of Medicine, Niigata University, 2-746, Asahimachi, Niigata 951-8518, Japan)

  • Rohana Chandrajith

    (Department of Geology, Faculty of Science, University of Peradeniya, Kandy 20400, Sri Lanka)

  • Nishantha Nanayakkara

    (Transplant and Dialysis Unit, Teaching Hospital, Kandy 20000, Sri Lanka)

Abstract

Symptom burden and health-related quality of life (HRQOL) are important predictors of how a disease affects patients’ lives, especially for endemic health problems such as chronic kidney disease of uncertain etiology (CKDu). Our study describes symptom burden, HRQOL, and associated demographic and clinical variables in CKDu patients in the Girandurukotte area, Sri Lanka. A cross-sectional study included 120 CKDu patients attending the renal clinic in the endemic area. The instruments applied were the Kidney Disease Quality of Life—Short Form (KDQOL-SF TM ) version 1.3 and CKD Symptom Index—Sri Lanka. Socio-demographic, disease-related, and anthropometric variables were also investigated. The mean age of patients was 61.87 (SD 11.31), while 69.2% were male. The mean glomerular filtration rate was 28.17 (SD 14.03) mL/min/1.73 min 2 , and 70.8% were anemic. Bone/joint pain was the most experienced symptom while the median number of symptoms reported by patients was 5 (IQR 3–7). The mean symptom burden, physical component summary, mental component summary, and kidney-disease-specific component scores were 12.71 (SD 10.45), 68.63 (SD 19.58), 78.53 (SD 18.78), and 81.57 (SD 5.86), respectively. Age was found to be a significant predictor of HRQOL, while hemoglobin level and being a farmer were significant predictors of symptom burden. Our data indicate that CKDu patients in all stages experience at least one symptom affecting all aspects of HRQOL.

Suggested Citation

  • Hansani Madushika Abeywickrama & Swarna Wimalasiri & Yu Koyama & Mieko Uchiyama & Utako Shimizu & Nahoko Kakihara & Rohana Chandrajith & Nishantha Nanayakkara, 2020. "Quality of Life and Symptom Burden among Chronic Kidney Disease of Uncertain Etiology (CKDu) Patients in Girandurukotte, Sri Lanka," IJERPH, MDPI, vol. 17(11), pages 1-16, June.
    • Handle: RePEc:gam:jijerp:v:17:y:2020:i:11:p:4041-:d:367949
    as

    Download full text from publisher

    File URL: https://www.mdpi.com/1660-4601/17/11/4041/pdf
    Download Restriction: no
    File URL: https://www.mdpi.com/1660-4601/17/11/4041/
    Download Restriction: no
    ---><---

    References listed on IDEAS

    as
    1. Channa Jayasumana & Sarath Gunatilake & Priyantha Senanayake, 2014. "Glyphosate, Hard Water and Nephrotoxic Metals: Are They the Culprits Behind the Epidemic of Chronic Kidney Disease of Unknown Etiology in Sri Lanka?," IJERPH, MDPI, vol. 11(2), pages 1-23, February.
    Full references (including those not matched with items on IDEAS)

    Citations

    Citations are extracted by the CitEc Project, subscribe to its RSS feed for this item.
    as


    Cited by:

    1. Thalwaththe Gedara Nadeeka Shayamalie Gunarathne & Li Yoong Tang & Soo Kun Lim & Nishantha Nanayakkara & Hewaratne Dassanayakege Wimala Thushari Damayanthi & Khatijah L. Abdullah, 2022. "Factors Associated with Symptom Burden in Adults with Chronic Kidney Disease Undergoing Hemodialysis: A Prospective Study," IJERPH, MDPI, vol. 19(9), pages 1-13, May.
    2. Khanh Vuong Diem Doan & Hien Thi Minh Nguyen & Nhi Thi Hong Nguyen & Khoa Cao Dang & Shwu-Huey Yang & Tuyen Van Duong, 2020. "Associations of Socio-Demographic, Clinical and Biochemical Parameters with Healthcare Cost, Health- and Renal-Related Quality of Life in Hemodialysis Patients: A Clinical Observational Study," IJERPH, MDPI, vol. 17(18), pages 1-15, September.
    3. I. D. U. H. Piyathilake & J. L. P. C. Randika & R. M. K. T. Rathnayaka & E. P. N. Udayakumara & L. V. Ranaweera & S. K. Gunatilake & C. B. Dissanayake, 2022. "Socio-economic determinants of Chronic Kidney Diseases of uncertain etiology (CKDu) in the Uva Province, Sri Lanka: a cross-sectional study," Journal of Environmental Studies and Sciences, Springer;Association of Environmental Studies and Sciences, vol. 12(4), pages 782-793, December.

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.
    1. Cecilia J. Sorensen & Lyndsay Krisher & Jaime Butler-Dawson & Miranda Dally & Lynn Dexter & Claudia Asensio & Alex Cruz & Lee S. Newman, 2020. "Workplace Screening Identifies Clinically Significant and Potentially Reversible Kidney Injury in Heat-Exposed Sugarcane Workers," IJERPH, MDPI, vol. 17(22), pages 1-17, November.
    2. Jaime Rendon-von Osten & Ricardo Dzul-Caamal, 2017. "Glyphosate Residues in Groundwater, Drinking Water and Urine of Subsistence Farmers from Intensive Agriculture Localities: A Survey in Hopelchén, Campeche, Mexico," IJERPH, MDPI, vol. 14(6), pages 1-13, June.
    3. Kuan Y. Chang & I-Wen Wu & Bo-Ruei Huang & Jih-Gau Juang & Jia-Chyi Wu & Su-Wei Chang & Chung Cheng Chang, 2018. "Associations between Water Quality Measures and Chronic Kidney Disease Prevalence in Taiwan," IJERPH, MDPI, vol. 15(12), pages 1-15, December.
    4. Sarath Gunatilake & Stephanie Seneff & Laura Orlando, 2019. "Glyphosate’s Synergistic Toxicity in Combination with Other Factors as a Cause of Chronic Kidney Disease of Unknown Origin," IJERPH, MDPI, vol. 16(15), pages 1-26, July.
    5. I. D. U. H. Piyathilake & J. L. P. C. Randika & R. M. K. T. Rathnayaka & E. P. N. Udayakumara & L. V. Ranaweera & S. K. Gunatilake & C. B. Dissanayake, 2022. "Socio-economic determinants of Chronic Kidney Diseases of uncertain etiology (CKDu) in the Uva Province, Sri Lanka: a cross-sectional study," Journal of Environmental Studies and Sciences, Springer;Association of Environmental Studies and Sciences, vol. 12(4), pages 782-793, December.
    6. Hasnain Iftikhar & Murad Khan & Zardad Khan & Faridoon Khan & Huda M Alshanbari & Zubair Ahmad, 2023. "A Comparative Analysis of Machine Learning Models: A Case Study in Predicting Chronic Kidney Disease," Sustainability, MDPI, vol. 15(3), pages 1-13, February.
    7. Joshua W. Schaeffer & John L. Adgate & Stephen J. Reynolds & Jaime Butler-Dawson & Lyndsay Krisher & Miranda Dally & Richard J. Johnson & Katherine A. James & Diana Jaramillo & Lee S. Newman, 2020. "A Pilot Study to Assess Inhalation Exposures among Sugarcane Workers in Guatemala: Implications for Chronic Kidney Disease of Unknown Origin," IJERPH, MDPI, vol. 17(16), pages 1-15, August.

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:gam:jijerp:v:17:y:2020:i:11:p:4041-:d:367949. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: MDPI Indexing Manager (email available below). General contact details of provider: https://www.mdpi.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.