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Early Lifestyle Interventions in People with Impaired Glucose Tolerance in Northern Colombia: The DEMOJUAN Project

Author

Listed:
  • Noël C. Barengo

    (Department of Medical and Population Health Research, Herbert Wertheim College of Medicine, Florida International University, Miami, FL 33178, USA
    Department of Public Health, Faculty of Medicine, University of Helsinki, 00100 Helsinki, Finland)

  • Tania Acosta

    (Department of Public Health, Universidad del Norte, Barranquilla 080001, Colombia)

  • Astrid Arrieta

    (Centro de Investigation Sanitaria, Barranquilla 080001, Colombia)

  • Carlos Ricaurte

    (Centro de Investigation Sanitaria, Barranquilla 080001, Colombia)

  • Dins Smits

    (Faculty of Medicine, Riga Stradins University, LV-1007 Riga, Latvia)

  • Karen Florez

    (Departamento de Matemáticas y Estadística, Universidad del Norte, Barranquilla 080001, Colombia)

  • Jaakko O. Tuomilehto

    (Department of Public Health, Faculty of Medicine, University of Helsinki, 00100 Helsinki, Finland
    Department of Public Health Solutions, National Institute for Health and Welfare, 00271 Helsinki, Finland
    Saudi Diabetes Research Group, King Abdulaziz University, Jeddah 21589, Saudi Arabia)

Abstract

Background: The objective of the demonstration project for type 2 diabetes prevention in the Barranquilla and Juan Mina (DEMOJUAN) study was to investigate the extent to which it is possible to reach normal glucose metabolism with early lifestyle interventions in people at high risk of type 2 diabetes (prediabetes), compared with those who receive standard usual care. Methods: DEMOJUAN was a randomized controlled trial conducted in Juan Mina and Barranquilla, Northern Colombia. Eligible participants were randomized into one of three groups (control group, initial nutritional intervention, and initial physical activity intervention). The duration of the intervention was 24 months. The main study outcome in the present analysis was reversion to normoglycemia. Relative risks and their corresponding 95% confidence intervals were calculated for reversal to normoglycemia and T2D incidence. Results: There was no statistically significant association between the intervention groups and reversion to normoglycemia. The relative risk of reversion to normoglycemia was 0.88 (95% CI 0.70–1.12) for the initial nutritional intervention group participants and 0.95 (95% CI 0.75–1.20) for the initial physical activity intervention group participants. Conclusions: Our study did not find any statistically significant differences in reversion to normoglycemia or the development of type 2 diabetes between the intervention groups and the control group in this population.

Suggested Citation

  • Noël C. Barengo & Tania Acosta & Astrid Arrieta & Carlos Ricaurte & Dins Smits & Karen Florez & Jaakko O. Tuomilehto, 2019. "Early Lifestyle Interventions in People with Impaired Glucose Tolerance in Northern Colombia: The DEMOJUAN Project," IJERPH, MDPI, vol. 16(8), pages 1-13, April.
    • Handle: RePEc:gam:jijerp:v:16:y:2019:i:8:p:1403-:d:224092
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    References listed on IDEAS

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    1. Katri Hemiö & Auli Pölönen & Kirsti Ahonen & Mikko Kosola & Katriina Viitasalo & Jaana Lindström, 2014. "A Simple Tool for Diet Evaluation in Primary Health Care: Validation of a 16-Item Food Intake Questionnaire," IJERPH, MDPI, vol. 11(3), pages 1-15, March.
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