IDEAS home Printed from https://ideas.repec.org/a/gam/jagris/v12y2022i2p187-d736843.html
   My bibliography  Save this article

Using Next-Generation Sequencing Technology to Explore Genetic Pathways in Endophytic Fungi in the Syntheses of Plant Bioactive Metabolites

Author

Listed:
  • Monika Bielecka

    (Department of Pharmaceutical Biology and Biotechnology, Wroclaw Medical University, 50-556 Wroclaw, Poland)

  • Bartosz Pencakowski

    (Department of Pharmaceutical Biology and Biotechnology, Wroclaw Medical University, 50-556 Wroclaw, Poland)

  • Rosario Nicoletti

    (Council for Agricultural Research and Economics, Research Centre for Olive, Fruit and Citrus Crops, 81100 Caserta, Italy
    Department of Agricultural Sciences, University of Naples Federico II, 80055 Portici, Italy)

Abstract

Recent investigations carried out all over the world have disclosed the capacity of a multitude of endophytic fungal species/strains to produce bioactive compounds which are the same or structurally related to those synthesized by their host plants. This intriguing phenomenon has implemented huge research activity aimed at ascertaining the nature of the biological processes underlying this convergence, as well as to characterize the genetic bases of the biosynthetic schemes. Insights on these basic issues may support the biotechnological exploitation of wild strains, and their eventual improvement through genome editing. Aspects concerning the use of next generation sequencing technologies for the comparative elucidation of the biosynthetic pathways operating in endophytic fungi and their host plants are reviewed in this paper in view of applicative perspectives. Our literature search yielded 21 references dealing with at least 26 strains which have been the subject of experimental activities involving massively parallel genome and transcriptome sequencing methods in the last eight years.

Suggested Citation

  • Monika Bielecka & Bartosz Pencakowski & Rosario Nicoletti, 2022. "Using Next-Generation Sequencing Technology to Explore Genetic Pathways in Endophytic Fungi in the Syntheses of Plant Bioactive Metabolites," Agriculture, MDPI, vol. 12(2), pages 1-18, January.
    • Handle: RePEc:gam:jagris:v:12:y:2022:i:2:p:187-:d:736843
    as

    Download full text from publisher

    File URL: https://www.mdpi.com/2077-0472/12/2/187/pdf
    Download Restriction: no
    File URL: https://www.mdpi.com/2077-0472/12/2/187/
    Download Restriction: no
    ---><---

    More about this item

    Keywords

    ;
    ;
    ;
    ;
    ;
    ;
    ;
    ;

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:gam:jagris:v:12:y:2022:i:2:p:187-:d:736843. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: MDPI Indexing Manager (email available below). General contact details of provider: https://www.mdpi.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.