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Racial inequities in the incidence of major adverse cardiovascular events in ELSA-Brasil cohort: the mediating role of weathering

Author

Listed:
  • Machado, Amanda Viana
  • Barreto, Sandhi Maria
  • Padilha dos Reis, Rodrigo Citton
  • Giatti, Luana
  • Alvim Matos, Sheila Maria
  • Patrão, Ana Luísa
  • Needham, Belinda L.
  • Camelo, Lidyane V.

Abstract

The weathering hypothesis proposes that chronic exposure to social disadvantage leads to earlier onset of age-related diseases, explaining, in part, greater CVD disadvantages of racialized groups. The investigation of such a hypothesis is incipient in Brazil, a society strongly marked by racism. We investigated whether racism is associated with incidence of major adverse cardiovascular events (MACE) and the extent to which weathering explained this association in Brazilian adults.

Suggested Citation

  • Machado, Amanda Viana & Barreto, Sandhi Maria & Padilha dos Reis, Rodrigo Citton & Giatti, Luana & Alvim Matos, Sheila Maria & Patrão, Ana Luísa & Needham, Belinda L. & Camelo, Lidyane V., 2025. "Racial inequities in the incidence of major adverse cardiovascular events in ELSA-Brasil cohort: the mediating role of weathering," Social Science & Medicine, Elsevier, vol. 383(C).
    • Handle: RePEc:eee:socmed:v:383:y:2025:i:c:s027795362500752x
    DOI: 10.1016/j.socscimed.2025.118421
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    References listed on IDEAS

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    1. Dóra Chor & Antonio Luiz Pinho Ribeiro & Marilia Sá Carvalho & Bruce Bartholow Duncan & Paulo Andrade Lotufo & Aline Araújo Nobre & Estela Mota Lima Leão de Aquino & Maria Inês Schmidt & Rosane Härter, 2015. "Prevalence, Awareness, Treatment and Influence of Socioeconomic Variables on Control of High Blood Pressure: Results of the ELSA-Brasil Study," PLOS ONE, Public Library of Science, vol. 10(6), pages 1-14, June.
    2. Kaufman, Jay S., 2008. "Epidemiologic analysis of racial/ethnic disparities: Some fundamental issues and a cautionary example," Social Science & Medicine, Elsevier, vol. 66(8), pages 1659-1669, April.
    3. Morgan E. Levine & Eileen M. Crimmins, 2018. "Is 60 the New 50? Examining Changes in Biological Age Over the Past Two Decades," Demography, Springer;Population Association of America (PAA), vol. 55(2), pages 387-402, April.
    4. repec:plo:pone00:0216653 is not listed on IDEAS
    5. Tyler J. VanderWeele & Eric J. Tchetgen Tchetgen, 2017. "Mediation analysis with time varying exposures and mediators," Journal of the Royal Statistical Society Series B, Royal Statistical Society, vol. 79(3), pages 917-938, June.
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