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Folding kinetics of two-state proteins based on the model of general random walk in native contact number space

Author

Listed:
  • Guo, J.S.
  • Mi, D.
  • Sun, Y.Q.

Abstract

We investigated the folding kinetics of a series of two-state proteins by using the model of general random walk in native contact number space, and derive the observed linear relationship between the logarithms of the folding rate constants and the numbers of native contacts from “kinetic viewpoint”. The protein folding speed limit and stability in this model are consistent with experimental observations.

Suggested Citation

  • Guo, J.S. & Mi, D. & Sun, Y.Q., 2010. "Folding kinetics of two-state proteins based on the model of general random walk in native contact number space," Physica A: Statistical Mechanics and its Applications, Elsevier, vol. 389(4), pages 761-766.
    • Handle: RePEc:eee:phsmap:v:389:y:2010:i:4:p:761-766
    DOI: 10.1016/j.physa.2009.10.026
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