IDEAS home Printed from https://ideas.repec.org/a/eee/phsmap/v318y2003i1p137-143.html
   My bibliography  Save this article

Punctuated evolution for the quasispecies model

Author

Listed:
  • Krug, Joachim
  • Karl, Christian

Abstract

Biological evolution in a sequence space with random fitnesses is studied within Eigen's quasispecies model. A strong selection limit is employed, in which the population resides at a single sequence at all times. Evolutionary trajectories start at a randomly chosen sequence and proceed to the global fitness maximum through a small number of intermittent jumps. The distribution of the total evolution time displays a universal power law tail with exponent −2. Simulations show that the evolutionary dynamics is very well represented by a simplified shell model, in which the sub-populations at local fitness maxima grow independently. The shell model allows for highly efficient simulations, and provides a simple geometric picture of the evolutionary trajectories.

Suggested Citation

  • Krug, Joachim & Karl, Christian, 2003. "Punctuated evolution for the quasispecies model," Physica A: Statistical Mechanics and its Applications, Elsevier, vol. 318(1), pages 137-143.
    • Handle: RePEc:eee:phsmap:v:318:y:2003:i:1:p:137-143
    DOI: 10.1016/S0378-4371(02)01417-6
    as

    Download full text from publisher

    File URL: http://www.sciencedirect.com/science/article/pii/S0378437102014176
    Download Restriction: Full text for ScienceDirect subscribers only. Journal offers the option of making the article available online on Science direct for a fee of $3,000
    File URL: https://libkey.io/10.1016/S0378-4371(02)01417-6?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    As the access to this document is restricted, you may want to search for a different version of it.

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:eee:phsmap:v:318:y:2003:i:1:p:137-143. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Catherine Liu (email available below). General contact details of provider: http://www.journals.elsevier.com/physica-a-statistical-mechpplications/ .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.