IDEAS home Printed from https://ideas.repec.org/a/eee/matcom/v188y2021icp389-403.html
   My bibliography  Save this article

Computational modeling of the effect of blood flow and dual phase lag on tissue temperature during tumor treatment by magnetic hyperthermia

Author

Listed:
  • Bera, A.
  • Dutta, S.
  • Misra, J.C.
  • Shit, G.C.

Abstract

This paper is devoted to the development of a mathematical model and its computational analysis targeted at investigating the effects of dual-phase lag on the heating protocol of tumor tissue by the method of electromagnetic hyperthermia. The model comprises two layers, one of them being the vessel layer in which blood flows under the action of a pressure gradient and an external magnetic field, while the other is a tissue layer containing a small rectangular tumor. The tumor tissue is heated by the periodic nature of metabolic and external heat sources. Two phase lags due to the presence of temperature gradient and heat flux are treated to observe the effect of faster heating phenomena. The wave equation representing bioheat transfer in the tissue layer is considered. The problem has been solved directly by employing a suitable finite difference numerical tool. The study shows that the phase lag caused by heat flux is more effective for heating the tumor than the phase lag due to the temperature gradient, and further that transversely applied magnetic field to the blood flow has a limited impact on enhancing the tumor temperature.

Suggested Citation

  • Bera, A. & Dutta, S. & Misra, J.C. & Shit, G.C., 2021. "Computational modeling of the effect of blood flow and dual phase lag on tissue temperature during tumor treatment by magnetic hyperthermia," Mathematics and Computers in Simulation (MATCOM), Elsevier, vol. 188(C), pages 389-403.
    • Handle: RePEc:eee:matcom:v:188:y:2021:i:c:p:389-403
    DOI: 10.1016/j.matcom.2021.04.020
    as

    Download full text from publisher

    File URL: http://www.sciencedirect.com/science/article/pii/S037847542100152X
    Download Restriction: Full text for ScienceDirect subscribers only
    File URL: https://libkey.io/10.1016/j.matcom.2021.04.020?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    As the access to this document is restricted, you may want to search for a different version of it.

    References listed on IDEAS

    as
    1. Abbasi, Ghasem & Malek, Alaeddin, 2019. "Hyperthermia cancer therapy by domain decomposition methods using strongly continuous semigroups," Mathematics and Computers in Simulation (MATCOM), Elsevier, vol. 165(C), pages 1-12.
    2. Shit, G.C. & Maiti, S. & Roy, M. & Misra, J.C., 2019. "Pulsatile flow and heat transfer of blood in an overlapping vibrating atherosclerotic artery: A numerical study," Mathematics and Computers in Simulation (MATCOM), Elsevier, vol. 166(C), pages 432-450.
    Full references (including those not matched with items on IDEAS)

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.
    1. Yihao Wu & Hui Xing & Qingyu Zhang & Dongke Sun, 2022. "Numerical Study on Dynamics of Blood Cell Migration and Deformation in Atherosclerotic Vessels," Mathematics, MDPI, vol. 10(12), pages 1-13, June.

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:eee:matcom:v:188:y:2021:i:c:p:389-403. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Catherine Liu (email available below). General contact details of provider: http://www.journals.elsevier.com/mathematics-and-computers-in-simulation/ .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.