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Dynamic transition on the seizure-like neuronal activity by astrocytic calcium channel block

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  • Li, Jiajia
  • Wang, Rong
  • Du, Mengmeng
  • Tang, Jun
  • Wu, Ying

Abstract

The involvement of astrocytes in neuronal firing dynamics is becoming increasingly evident. In this study, we used a classical hippocampal tripartite synapse model consisting of soma-dendrite coupled neuron models and a Hodgkin–Huxley-like astrocyte model, to investigate the seizure-like firing in the somatic neuron induced by the over-expressed neuronal N-methyl-d-aspartate (NMDA) receptors. Based on this model, we further investigated the effect of the astrocytic channel block on the neuronal firing through a bifurcation analysis. Results show that blocking inositol-1,4,5-triphosphate(IP3)-dependent calcium channel in astrocytes efficiently suppresses the astrocytic calcium oscillation, which in turn suppresses the seizure-like firing in the neuron.

Suggested Citation

  • Li, Jiajia & Wang, Rong & Du, Mengmeng & Tang, Jun & Wu, Ying, 2016. "Dynamic transition on the seizure-like neuronal activity by astrocytic calcium channel block," Chaos, Solitons & Fractals, Elsevier, vol. 91(C), pages 702-708.
    • Handle: RePEc:eee:chsofr:v:91:y:2016:i:c:p:702-708
    DOI: 10.1016/j.chaos.2016.08.009
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    1. X. J. Sun & J. Z. Lei & M. Perc & Q. S. Lu & S. J. Lv, 2011. "Effects of channel noise on firing coherence of small-world Hodgkin-Huxley neuronal networks," The European Physical Journal B: Condensed Matter and Complex Systems, Springer;EDP Sciences, vol. 79(1), pages 61-66, January.
    2. Schmid, Gerhard & Goychuk, Igor & Hänggi, Peter, 2004. "Controlling the spiking activity in excitable membranes via poisoning," Physica A: Statistical Mechanics and its Applications, Elsevier, vol. 344(3), pages 665-670.
    3. Wang, Qingyun & Perc, Matjaž & Duan, Zhisheng & Chen, Guanrong, 2010. "Impact of delays and rewiring on the dynamics of small-world neuronal networks with two types of coupling," Physica A: Statistical Mechanics and its Applications, Elsevier, vol. 389(16), pages 3299-3306.
    4. Wang, Qingyun & Lu, Qishao & Chen, GuanRong & feng, Zhaosheng & Duan, LiXia, 2009. "Bifurcation and synchronization of synaptically coupled FHN models with time delay," Chaos, Solitons & Fractals, Elsevier, vol. 39(2), pages 918-925.
    5. Uzuntarla, Muhammet & Uzun, Rukiye & Yilmaz, Ergin & Ozer, Mahmut & Perc, Matjaž, 2013. "Noise-delayed decay in the response of a scale-free neuronal network," Chaos, Solitons & Fractals, Elsevier, vol. 56(C), pages 202-208.
    6. Ghanim Ullah & Steven J Schiff, 2010. "Assimilating Seizure Dynamics," PLOS Computational Biology, Public Library of Science, vol. 6(5), pages 1-12, May.
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    Cited by:

    1. Zhou, Ping & Yao, Zhao & Ma, Jun & Zhu, Zhigang, 2021. "A piezoelectric sensing neuron and resonance synchronization between auditory neurons under stimulus," Chaos, Solitons & Fractals, Elsevier, vol. 145(C).
    2. Li, Xiang & Zhang, Suxia & Liu, Xijun & Wang, Xiaojing & Zhou, Anqi & Liu, Peng, 2018. "Important role of MAMs in bifurcation and coherence resonance of calcium oscillations," Chaos, Solitons & Fractals, Elsevier, vol. 106(C), pages 131-140.
    3. Yu, Yangyang & Yuan, Zhixuan & Li, Jiajia & Wu, Ying, 2023. "Dynamic analysis of epileptic seizures caused by energy failure after ischemic stroke," Chaos, Solitons & Fractals, Elsevier, vol. 176(C).
    4. Xiao, Fangli & Fu, Ziying & Jia, Ya & Yang, Lijian, 2023. "Resonance effects in neuronal-astrocyte model with ion channel blockage," Chaos, Solitons & Fractals, Elsevier, vol. 166(C).

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