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The Use of Human Immunodeficiency Virus Diagnosis Information in Monitoring the Acquired Immune Deficiency Syndrome Epidemic

Author

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  • O. O. Aalen
  • V. T. Farewell
  • D. De Angelis
  • N. E. DAY

Abstract

For acquired immune deficiency syndrome (AIDS) patients, information may be available on the time of diagnosis of human immunodeficiency virus (HIV) (first positive HIV antibody test) in addition to the time of AIDS diagnosis. This extra information may be incorporated into backcalculation of HIV infection curves. This also allows the estimation of the rate of HIV diagnosis among HIV‐infected individuals, a measure which is of obvious public health importance. A framework for this is described and then applied to data from England and Wales. Different exposure categories are compared. The incorporation of information on the total number of HIV diagnoses in specific exposure groups is also examined.

Suggested Citation

  • O. O. Aalen & V. T. Farewell & D. De Angelis & N. E. DAY, 1994. "The Use of Human Immunodeficiency Virus Diagnosis Information in Monitoring the Acquired Immune Deficiency Syndrome Epidemic," Journal of the Royal Statistical Society Series A, Royal Statistical Society, vol. 157(1), pages 3-16, January.
    • Handle: RePEc:bla:jorssa:v:157:y:1994:i:1:p:3-16
    DOI: 10.2307/2983501
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    Cited by:

    1. Francesco Brizzi & Paul J. Birrell & Martyn T. Plummer & Peter Kirwan & Alison E. Brown & Valerie C. Delpech & O. Noel Gill & Daniela Angelis, 2019. "Extending Bayesian back-calculation to estimate age and time specific HIV incidence," Lifetime Data Analysis: An International Journal Devoted to Statistical Methods and Applications for Time-to-Event Data, Springer, vol. 25(4), pages 757-780, October.
    2. A. Goubar & A. E. Ades & D. De Angelis & C. A. McGarrigle & C. H. Mercer & P. A. Tookey & K. Fenton & O. N. Gill, 2008. "Estimates of human immunodeficiency virus prevalence and proportion diagnosed based on Bayesian multiparameter synthesis of surveillance data," Journal of the Royal Statistical Society Series A, Royal Statistical Society, vol. 171(3), pages 541-580, June.

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