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Improved Estimation of the Noncentrality Parameter Distribution from a Large Number of t-Statistics, with Applications to False Discovery Rate Estimation in Microarray Data Analysis

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  • Long Qu
  • Dan Nettleton
  • Jack C. M. Dekkers

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  • Long Qu & Dan Nettleton & Jack C. M. Dekkers, 2012. "Improved Estimation of the Noncentrality Parameter Distribution from a Large Number of t-Statistics, with Applications to False Discovery Rate Estimation in Microarray Data Analysis," Biometrics, The International Biometric Society, vol. 68(4), pages 1178-1187, December.
    • Handle: RePEc:bla:biomet:v:68:y:2012:i:4:p:1178-1187
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    File URL: http://hdl.handle.net/10.1111/j.1541-0420.2012.01764.x
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    References listed on IDEAS

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    1. Baolin Wu & Zhong Guan & Hongyu Zhao, 2006. "Parametric and Nonparametric FDR Estimation Revisited," Biometrics, The International Biometric Society, vol. 62(3), pages 735-744, September.
    2. David Ruppert & Dan Nettleton & J. T. Gene Hwang, 2007. "Exploring the Information in p-Values for the Analysis and Planning of Multiple-Test Experiments," Biometrics, The International Biometric Society, vol. 63(2), pages 483-495, June.
    3. Chen-An Tsai & Huey-miin Hsueh & James J. Chen, 2003. "Estimation of False Discovery Rates in Multiple Testing: Application to Gene Microarray Data," Biometrics, The International Biometric Society, vol. 59(4), pages 1071-1081, December.
    4. Yoav Benjamini & Yosef Hochberg, 2000. "On the Adaptive Control of the False Discovery Rate in Multiple Testing With Independent Statistics," Journal of Educational and Behavioral Statistics, , vol. 25(1), pages 60-83, March.
    5. Smyth Gordon K, 2004. "Linear Models and Empirical Bayes Methods for Assessing Differential Expression in Microarray Experiments," Statistical Applications in Genetics and Molecular Biology, De Gruyter, vol. 3(1), pages 1-28, February.
    6. Sun, Wenguang & Cai, T. Tony, 2007. "Oracle and Adaptive Compound Decision Rules for False Discovery Rate Control," Journal of the American Statistical Association, American Statistical Association, vol. 102, pages 901-912, September.
    7. Mette Langaas & Bo Henry Lindqvist & Egil Ferkingstad, 2005. "Estimating the proportion of true null hypotheses, with application to DNA microarray data," Journal of the Royal Statistical Society Series B, Royal Statistical Society, vol. 67(4), pages 555-572, September.
    8. Christopher Genovese & Larry Wasserman, 2002. "Operating characteristics and extensions of the false discovery rate procedure," Journal of the Royal Statistical Society Series B, Royal Statistical Society, vol. 64(3), pages 499-517, August.
    9. Jin, Jiashun & Cai, T. Tony, 2007. "Estimating the Null and the Proportion of Nonnull Effects in Large-Scale Multiple Comparisons," Journal of the American Statistical Association, American Statistical Association, vol. 102, pages 495-506, June.
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    Cited by:

    1. van Iterson Maarten & van de Wiel Mark A. & Boer Judith M. & de Menezes Renée X., 2013. "General power and sample size calculations for high-dimensional genomic data," Statistical Applications in Genetics and Molecular Biology, De Gruyter, vol. 12(4), pages 449-467, August.
    2. Zehetmayer Sonja & Graf Alexandra C. & Posch Martin, 2015. "Sample size reassessment for a two-stage design controlling the false discovery rate," Statistical Applications in Genetics and Molecular Biology, De Gruyter, vol. 14(5), pages 429-442, November.

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