“Homeopathic Medicines for Rheumatoid Arthritis and Osteoarthritis: A Systematic Review of Materia Medica Evidence Following PRISMA Guidelinesâ€

Background: Rheumatoid Arthritis (RA) and Osteoarthritis (OA) are most frequent chronic joint diseases, resulting in pain, stiffness, and disability. Standard treatment provides symptomatic relief without likely cures. Homeopathy, based on individualized prescribing, has a potent foundation in Materia Medica, wherein medicines have been taken from provings and clinical confirmations. Classical Materia Medica can be systematically examined to elicit medicines most frequently indicated in arthritis. Objectives: To systematically review classical Homeopathic MateriaMedica texts in an attempt to identify and summarize homeopathic remedies for Rheumatoid Arthritis and Osteoarthritis. Methods: A systematic review was conducted using primary Homeopathic Materia Medica sources including Hahnemann’s Materia Medica Pura, Allen’s Encyclopaedia of Pure Materia Medica, Boericke’s Pocket Manual of Materia Medica, Clarke’s Dictionary of Practical Materia Medica, Kent’s Lectures on Homoeopathic Materia Medica, and Phatak’s Materia Medica. Remedies were taken into account if they outlined ≥3 arthritisspecific symptoms (pain, swelling, stiffness, deformity, modalities). Remedies in which there were vague or general musculoskeletal mentions without anything specific were excluded. The data were systematically extracted and tabled by remedy name, keynotes, modalities, and indications. The review proceeded as per PRISMA guidelines for reporting systematic review. Results: 120 remedies were scrutinized in all; 35 showed strong relevance to arthritis, and 15 remedies were shortlisted for critical analysis. The most indicatively advised remedies included Rhus toxicodendron, Bryonia alba, Causticum, Kali carbonicum, Colchicum autumnale, Guaiacum, Ledum palustre, Actaea spicata, and Arnica montana. These remedies all showed characteristic modalities and keynote symptoms reflecting RA or OA symptoms. Conclusion: This systematic review of Materia Medica reveals there are several remedies with common indications for Rheumatoid Arthritis and Osteoarthritis. Bryonia and Rhus tox were most commonly indicated, and Causticum and Kali Carb most resembled chronic progressive deformity and stiffness. There is good theory based upon this Materia Medica, but clinical trials would have to be performed to establish these findings as evidence-based practice inclusion.