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Ecological association of human papillomavirus vaccination with cervical dysplasia prevalence in the United States, 2007-2014

Author

Listed:
  • Flagg, E.W.
  • Torrone, E.A.
  • Weinstock, H.

Abstract

Objectives. To examine prevalence of low-and high-grade cervical lesions over time in a large cohort of US female adolescents and women. Methods. We used health care claims data from 9 million privately insured female patients aged 15 to 39years to estimate annual prevalence of cytologically detected cervical low-grade (LSIL) and high-grade squamous intraepithelial lesions (HSIL) and high-grade histologically detected cervical intraepithelial neoplasia grades 2 and 3 (CIN2+) during 2007 through 2014. Werestrictedanalysestothosewhoreceivedcervicalcancerscreeninginagivencalendar year. Results. Prevalence of HSIL and CIN2+ decreased significantly for those aged 15 to 19 years. Average annual percent change in prevalence in this group during 2007 through 2014 for HSIL and CIN2+ was-8.3% and-14.4%, respectively (P

Suggested Citation

  • Flagg, E.W. & Torrone, E.A. & Weinstock, H., 2016. "Ecological association of human papillomavirus vaccination with cervical dysplasia prevalence in the United States, 2007-2014," American Journal of Public Health, American Public Health Association, vol. 106(12), pages 2211-2218.
    • Handle: RePEc:aph:ajpbhl:10.2105/ajph.2016.303472_7
    DOI: 10.2105/AJPH.2016.303472
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