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Social, behavioral, and genetic linkages from adolescence into adulthood

Author

Listed:
  • Harris, K.M.
  • Halpern, C.T.
  • Hussey, J.
  • Whitsel, E.A.
  • Killeya-Jones, L.
  • Tabor, J.
  • Elder, G.
  • Hewitt, J.
  • Shanahan, M.
  • Williams, R.
  • Siegler, I.
  • Smolen, A.

Abstract

The influence of genetic factors on health and behavior is conditioned by social, cultural, institutional, and physical environments in which individuals live, work, and play. We encourage studies supporting multilevel integrative approaches to understanding these contributions to health, and describe the Add Health study as an exemplar. Add Health is a large sample of US adolescents in grades 7 to 12 in 1994- 1995 followed into adulthood with 4 in-home interviews and biomarker collections, including DNA. In addition to sampling multiple environments and measuring diverse social and health behavior, Add Health features a fully articulated behavioral genetic sample (3000 pairs) and ongoing genotyping of 12 000 archived samples. We illustrate approaches to understanding health through investigation of the interplay among biological, psychosocial, and physical, contextual, or cultural experiences.

Suggested Citation

  • Harris, K.M. & Halpern, C.T. & Hussey, J. & Whitsel, E.A. & Killeya-Jones, L. & Tabor, J. & Elder, G. & Hewitt, J. & Shanahan, M. & Williams, R. & Siegler, I. & Smolen, A., 2013. "Social, behavioral, and genetic linkages from adolescence into adulthood," American Journal of Public Health, American Public Health Association, vol. 103(SUPPL.1), pages 25-32.
    • Handle: RePEc:aph:ajpbhl:10.2105/ajph.2012.301181_7
    DOI: 10.2105/AJPH.2012.301181
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    Cited by:

    1. Lauren Gaydosh & Daniel W. Belsky & Benjamin W. Domingue & Jason D. Boardman & Kathleen Mullan Harris, 2018. "Father Absence and Accelerated Reproductive Development in Non-Hispanic White Women in the United States," Demography, Springer;Population Association of America (PAA), vol. 55(4), pages 1245-1267, August.
    2. Yi Zeng & Huashuai Chen & Xiaomin Liu & Rui Ye & Enjun Xie & Zhihua Chen & Jiehua Lu & Jianxin Li & Yaohua Tian & Ting Ni & Lars Bolund & Kenneth C. Land & Anatoliy Yashin & Angela M. O'Rand & Liang S, 2017. "Sex differences in genetic associations with longevity in Han Chinese: sex-stratified genome-wide association study and polygenic risk score analysis," MPIDR Working Papers WP-2017-004, Max Planck Institute for Demographic Research, Rostock, Germany.
    3. Jennifer B. Kane & Claire Margerison-Zilko, 2017. "Theoretical Insights into Preconception Social Conditions and Perinatal Health: The Role of Place and Social Relationships," Population Research and Policy Review, Springer;Southern Demographic Association (SDA), vol. 36(5), pages 639-669, October.

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