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Angiotensin-I Converting Enzyme Inhibitor Activity in Japanese Burdock Roots

Author

Listed:
  • Kawamura, Shougo
  • Murakami, Takayuki
  • Ishihara, Kohji
  • Masuoka, Noriyoshi

Abstract

Japanese burdock roots were extracted with aqueous methanol solution. A compound having the inhibitory activity of angiotensin I-converting enzyme (ACE)[EC 3.4.15.1] was purified and identified as nicotianamine, (2S, 3’S, 3”S)-N-[N-(3-amino-3-carboxypropyl)-3-amino-3-carboxypropyl]azetidine-2-carboxylic acid. The compound content in burdock roots and related food products were determined. Data revealed that burdock root is a good source of nicotianamine (NA).

Suggested Citation

  • Kawamura, Shougo & Murakami, Takayuki & Ishihara, Kohji & Masuoka, Noriyoshi, 2014. "Angiotensin-I Converting Enzyme Inhibitor Activity in Japanese Burdock Roots," Journal of Food Research, Canadian Center of Science and Education, vol. 4(2).
    • Handle: RePEc:ags:aesjfr:405245
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    File URL: https://ageconsearch.umn.edu/record/405245/files/43708-150210-2-PB.pdf
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