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A Deep Learning Framework for Multi Drug Side Effects Prediction with Drug Chemical Substructure

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  • Muhammad Asad Arshed, Shahzad Mumtaz, Omer Riaz, Waqas Sharif, Saima Abdullah

    (Department of Software Engineering, University of Management & Technology, Lahore, Pakistan. Department of Artificial Intelligence, The Islamia University of Bahawalpur, Bahawalpur, Pakistan. Department of Data Science, The Islamia University of Bahawalpur, Bahawalpur, Pakistan. Department of Information Technology, The Islamia University of Bahawalpur, Bahawalpur, Pakistan. Department of Computer Science, The Islamia University of Bahawalpur, Bahawalpur, Pakistan)

Abstract

Nowadays, side effects and adverse reactions of drugs are considered the major concern regarding public health. In the process of drug development, it is also considered the main cause of drug failure. Due to the major side effects, drugs are withdrawan from the market immediately. Therefore, in the drug discovery process, the prediction of side effects is a basic need to control the drug development cost and time as well as launching of an effective drug in the market in terms of patient health recovery. In this study, we have proposed a deep learning model named “DLMSE” for the prediction of multiple side effects of drugs with the chemical structure of drugs. As it is a common experience that a single drug can cause multiple side effects, that’s why we have proposed a deep learning model that can predict multiple side effects for a single drug. We have considered three side effects (Dizziness, Allergy, Headache) in this study. We have collected the drug side effects information from the SIDER database. We have achieved an accuracy of ‘0.9494’ with our multi-label classification based proposed model. The proposed model can be used in different stages of the drug development process

Suggested Citation

  • Muhammad Asad Arshed, Shahzad Mumtaz, Omer Riaz, Waqas Sharif, Saima Abdullah, 2022. "A Deep Learning Framework for Multi Drug Side Effects Prediction with Drug Chemical Substructure," International Journal of Innovations in Science & Technology, 50sea, vol. 4(1), pages 19-31, January.
    • Handle: RePEc:abq:ijist1:v:4:y:2022:i:1:p:19-31
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    References listed on IDEAS

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    1. Cristina Monteiro & Beatriz Dias & Maria Vaz-Patto, 2021. "Headache as an Adverse Reaction to the Use of Medication in the Elderly: A Pharmacovigilance Study," IJERPH, MDPI, vol. 18(5), pages 1-11, March.
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