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Drug Prices and Research and Development Investment Behavior in the Pharmaceutical Industry

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Author Info
Giaccotto, Carmelo
Santerre, Rexford E
Vernon, John A

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Abstract

This paper argues theoretically and shows empirically that pharmaceutical R&D spending increases with real drug prices, after holding constant other determinants of research and development (R&D). Specifically, an estimated elasticity suggests that a 10 percent increase in the growth of real drug prices is associated with nearly a 6 percent increase in the growth of R&D intensity. Simulations that are based on our multiple-regression model indicate that the capitalized value of pharmaceutical R&D spending would have been about 30 percent lower if the federal government had limited the rate of growth in drug price increases to the rate of growth in the general consumer price index during the period 1980-2001. Moreover, the results suggest that a drug price control regime would have resulted in 330--65 fewer new drugs, representing over one-third of all actual new drug launches brought to the global market during that time period.

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Publisher Info
Article provided by University of Chicago Press in its journal Journal of Law and Economics.

Volume (Year): 48 (2005)
Issue (Month): 1 (April)
Pages: 195-214
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Handle: RePEc:ucp:jlawec:y:2005:v:48:i:1:p:195-214

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  1. Joseph H. Golec & John A. Vernon, 2007. "Financial Risk in the Biotechnology Industry," NBER Working Papers 13604, National Bureau of Economic Research, Inc. [Downloadable!] (restricted)
  2. Joseph H. Golec & John A. Vernon, 2006. "European Pharmaceutical Price Regulation, Firm Profitability, and R&D Spending," NBER Working Papers 12676, National Bureau of Economic Research, Inc. [Downloadable!] (restricted)
  3. Katherine Sauer, 2008. "A model of parallel imports of pharmaceuticals with endogenous price controls," Economics Bulletin, Economics Bulletin, vol. 6(36), pages 1-8. [Downloadable!]
  4. William S. Comanor & Stuart O. Schweitzer, 2007. "Determinants of drug prices and expenditures," Managerial and Decision Economics, John Wiley & Sons, Ltd., vol. 28(4-5), pages 357-370. [Downloadable!]
  5. Malmberg, Claes, 2008. "R&D and financial systems: the determinants of R&D expenditures in the Swedish pharmaceutical industry," CIRCLE Electronic Working Paper Series 2008-01, CIRCLE (Centre for Innovation, Research and Competence in the Learning Economy), Lund University. [Downloadable!]
  6. Joseph Golec & John A. Vernon, 2007. "New estimates of pharmaceutical research and development spending by US-based firms from 1984 to 2003," Managerial and Decision Economics, John Wiley & Sons, Ltd., vol. 28(4-5), pages 481-483. [Downloadable!]
  7. Joseph Golec & John A. Vernon, 2007. "New estimates of pharmaceutical research and development spending by US-based firms from 1984 to 2003," Health Economics, John Wiley & Sons, Ltd., vol. 28(4-5), pages 481-483. [Downloadable!]
  8. William S. Comanor & Stuart O. Schweitzer, 2007. "Determinants of drug prices and expenditures," Health Economics, John Wiley & Sons, Ltd., vol. 28(4-5), pages 357-370. [Downloadable!]
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