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Determining factors of cities’ centrality in the interregional innovation networks of China’s biomedical industry

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  • Qin Ye

    (Shanghai Normal University)

  • Xiaolei Xu

    (Shanghai Normal University)

Abstract

This study analyzed the determinants of regions’ degree centrality as well as their variation over time in interregional innovation networks and compared the differences in factors between developed and less developed regions(core and periphery). Focusing on China’s biomedical industry, we used the prefecture-level invention co-patents data (2012–2017) to construct intercity networks and related cities’ centrality to sector-region-specific factors. We found: (1) A “convergence” process of regional embeddedness exists in innovation networks among cities. (2) The volume of national public funding for fundamental researches in the biomedical industry plays the most important role in cities’ centrality, regardless of developed or undeveloped cities. (3) For the developed cities’ centrality position, the intensity of intraregional collaboration in the biomedical industry is the secondary influencing factor, besides, other positive factors involve innovation performance, industrial market application, and cluster competitiveness, but it does not affect peripheral cities. (4) The second most influential factor in peripheral cities’ centrality is the number of biomedical firms. We concluded that despite the influence of path dependence, in the field of the analytical industry, China’s public funding for basic research has narrowed the gap in networking capability between the developed and backward cities.

Suggested Citation

  • Qin Ye & Xiaolei Xu, 2021. "Determining factors of cities’ centrality in the interregional innovation networks of China’s biomedical industry," Scientometrics, Springer;Akadémiai Kiadó, vol. 126(4), pages 2801-2819, April.
  • Handle: RePEc:spr:scient:v:126:y:2021:i:4:d:10.1007_s11192-020-03853-3
    DOI: 10.1007/s11192-020-03853-3
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    1. Markus Grillitsch & Josephine Rekers & Franz Tödtling, 2019. "When drivers of clusters shift scale from local towards global: What remains for regional innovation policy?," PEGIS geo-disc-2019_03, Institute for Economic Geography and GIScience, Department of Socioeconomics, Vienna University of Economics and Business.
    2. Clarysse, Bart & Wright, Mike & Bruneel, Johan & Mahajan, Aarti, 2014. "Creating value in ecosystems: Crossing the chasm between knowledge and business ecosystems," Research Policy, Elsevier, vol. 43(7), pages 1164-1176.
    3. G. M.P. Swann, 2009. "The Economics of Innovation," Books, Edward Elgar Publishing, number 13211.
    4. Gilsing, Victor & Nooteboom, Bart & Vanhaverbeke, Wim & Duysters, Geert & van den Oord, Ad, 2008. "Network embeddedness and the exploration of novel technologies: Technological distance, betweenness centrality and density," Research Policy, Elsevier, vol. 37(10), pages 1717-1731, December.
    5. Shengjun Zhu & Canfei He & Yi Zhou, 2017. "How to jump further and catch up? Path-breaking in an uneven industry space," Journal of Economic Geography, Oxford University Press, vol. 17(3), pages 521-545.
    6. Robert Huggins & Hiro Izushi & Daniel Prokop, 2019. "Regional advantage and the geography of networks: Explaining global–local knowledge sourcing patterns," Papers in Regional Science, Wiley Blackwell, vol. 98(4), pages 1567-1584, August.
    7. Philip McCann & Raquel Ortega-Argilés, 2013. "Modern regional innovation policy," Cambridge Journal of Regions, Economy and Society, Cambridge Political Economy Society, vol. 6(2), pages 187-216.
    8. Garri Raagmaa & Anne Keerberg, 2017. "Regional higher education institutions in regional leadership and development," Regional Studies, Taylor & Francis Journals, vol. 51(2), pages 260-272, February.
    9. Alexander Berman & Alba Marino & Ram Mudambi, 2020. "The global connectivity of regional innovation systems in Italy: a core–periphery perspective," Regional Studies, Taylor & Francis Journals, vol. 54(5), pages 677-691, May.
    10. Asheim, Bjorn T. & Coenen, Lars, 2005. "Knowledge bases and regional innovation systems: Comparing Nordic clusters," Research Policy, Elsevier, vol. 34(8), pages 1173-1190, October.
    11. Yutao Sun & Kai Liu, 2016. "Proximity effect, preferential attachment and path dependence in inter-regional network: a case of China’s technology transaction," Scientometrics, Springer;Akadémiai Kiadó, vol. 108(1), pages 201-220, July.
    12. Guan, Jiancheng & Zhang, Jingjing & Yan, Yan, 2015. "The impact of multilevel networks on innovation," Research Policy, Elsevier, vol. 44(3), pages 545-559.
    13. Bjørn Asheim & Lars Coenen & Jan Vang, 2007. "Face-to-Face, Buzz, and Knowledge Bases: Sociospatial Implications for Learning, Innovation, and Innovation Policy," Environment and Planning C, , vol. 25(5), pages 655-670, October.
    14. De Marchi, Valentina, 2012. "Environmental innovation and R&D cooperation: Empirical evidence from Spanish manufacturing firms," Research Policy, Elsevier, vol. 41(3), pages 614-623.
    15. Davide Consoli & Andrea Mina, 2009. "An evolutionary perspective on health innovation systems," Journal of Evolutionary Economics, Springer, vol. 19(2), pages 297-319, April.
    16. Attila Varga & Dimitrios Pontikakis & George Chorafakis, 2014. "Metropolitan Edison and cosmopolitan Pasteur? Agglomeration and interregional research network effects on European R&D productivity," Journal of Economic Geography, Oxford University Press, vol. 14(2), pages 229-263.
    17. Franzoni, Chiara & Sauermann, Henry, 2014. "Crowd science: The organization of scientific research in open collaborative projects," Research Policy, Elsevier, vol. 43(1), pages 1-20.
    18. Allen J. Scott & Michael Storper, 2015. "The Nature of Cities: The Scope and Limits of Urban Theory," International Journal of Urban and Regional Research, Wiley Blackwell, vol. 39(1), pages 1-15, January.
    19. Anne Ter Wal & Ron Boschma, 2011. "Co-evolution of Firms, Industries and Networks in Space," Regional Studies, Taylor & Francis Journals, vol. 45(7), pages 919-933.
    20. Sverre J. Herstad & Bernd Ebersberger, 2015. "On the Link between Urban Location and the Involvement of Knowledge-Intensive Business Services Firms in Collaboration Networks," Regional Studies, Taylor & Francis Journals, vol. 49(7), pages 1160-1175, July.
    21. David Marek & Jiří Blažek, 2016. "The challenge of breaking the academia--business firewall in Czechia: comparing the role of differentiated knowledge bases in collaborative R&D projects," European Planning Studies, Taylor & Francis Journals, vol. 24(4), pages 809-831.
    22. Arne Isaksen, 2015. "Industrial development in thin regions: trapped in path extension?," Journal of Economic Geography, Oxford University Press, vol. 15(3), pages 585-600.
    23. Oliver Plum & Robert Hassink, 2011. "Comparing knowledge networking in different knowledge bases in Germany," Papers in Regional Science, Wiley Blackwell, vol. 90(2), pages 355-371, June.
    24. Helen Lawton Smith, 2007. "Universities, Innovation, and Territorial Development: A Review of the Evidence," Environment and Planning C, , vol. 25(1), pages 98-114, February.
    25. Markus Grillitsch & Magnus Nilsson, 2015. "Innovation in peripheral regions: Do collaborations compensate for a lack of local knowledge spillovers?," The Annals of Regional Science, Springer;Western Regional Science Association, vol. 54(1), pages 299-321, January.
    26. Jean-Paul D. Addie & Mariarosalba Angrisani & Stefano De Falco, 2018. "University-led innovation in and for peripheral urban areas: new approaches in Naples, Italy and Newark, NJ, US," European Planning Studies, Taylor & Francis Journals, vol. 26(6), pages 1181-1201, June.
    27. Timo Mitze & Falk Strotebeck, 2018. "Centrality and get-richer mechanisms in interregional knowledge networks," Regional Studies, Taylor & Francis Journals, vol. 52(11), pages 1477-1489, November.
    28. Stefan Töpfer & Uwe Cantner & Holger Graf, 2019. "Structural dynamics of innovation networks in German Leading-Edge Clusters," The Journal of Technology Transfer, Springer, vol. 44(6), pages 1816-1839, December.
    29. Johannes Glückler, 2014. "How controversial innovation succeeds in the periphery? A network perspective of BASF Argentina," Journal of Economic Geography, Oxford University Press, vol. 14(5), pages 903-927.
    30. Iris Wanzenböck & Thomas Scherngell & Thomas Brenner, 2014. "Embeddedness of regions in European knowledge networks: a comparative analysis of inter-regional R&D collaborations, co-patents and co-publications," The Annals of Regional Science, Springer;Western Regional Science Association, vol. 53(2), pages 337-368, September.
    31. Kevin Zheng Zhou & Caroline Bingxin Li, 2012. "How knowledge affects radical innovation: Knowledge base, market knowledge acquisition, and internal knowledge sharing," Strategic Management Journal, Wiley Blackwell, vol. 33(9), pages 1090-1102, September.
    32. Daniel Nepelski & Giuditta De Prato, 2018. "The structure and evolution of ICT global innovation network," Industry and Innovation, Taylor & Francis Journals, vol. 25(10), pages 940-965, November.
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