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Costs of illness of multiple sclerosis in Sweden: a population-based register study of people of working age

Author

Listed:
  • Hanna Gyllensten

    (Karolinska Institutet
    University of Gothenburg)

  • Michael Wiberg

    (Karolinska Institutet
    Swedish Social Insurance Agency)

  • Kristina Alexanderson

    (Karolinska Institutet)

  • Anders Norlund

    (Karolinska Institutet)

  • Emilie Friberg

    (Karolinska Institutet)

  • Jan Hillert

    (Karolinska Institutet)

  • Olivia Ernstsson

    (Karolinska Institutet
    Karolinska Institutet)

  • Petter Tinghög

    (Karolinska Institutet
    Red Cross University College)

Abstract

Background Multiple sclerosis (MS) causes work disability and healthcare resource use, but little is known about the distribution of the associated costs to society. Objectives We estimated the cost of illness (COI) of working-aged individuals with MS, from the societal perspective, overall and in different groups. Methods A population-based study was conducted, using data linked from several nationwide registers, on 14,077 individuals with MS, aged 20–64 years and living in Sweden. Prevalence-based direct and indirect costs in 2010 were calculated, including costs for prescription drug use, specialized healthcare, sick leave, and disability pension. Results The estimated COI of all the MS patients were SEK 3950 million, of which 75% were indirect costs. MS was the main diagnosis for resource use, causing 38% of healthcare costs and 67% of indirect costs. The distribution of costs was skewed, in which less than 25% of the patients accounted for half the total COI. Conclusions Indirect costs contributed to approximately 75% of the estimated overall COI of MS patients of working age in Sweden. MS was the main diagnosis for more than half of the estimated COI in this patient group. Further studies are needed to gain knowledge on development of costs over time during the MS disease course.

Suggested Citation

  • Hanna Gyllensten & Michael Wiberg & Kristina Alexanderson & Anders Norlund & Emilie Friberg & Jan Hillert & Olivia Ernstsson & Petter Tinghög, 2018. "Costs of illness of multiple sclerosis in Sweden: a population-based register study of people of working age," The European Journal of Health Economics, Springer;Deutsche Gesellschaft für Gesundheitsökonomie (DGGÖ), vol. 19(3), pages 435-446, April.
    • Handle: RePEc:spr:eujhec:v:19:y:2018:i:3:d:10.1007_s10198-017-0894-6
    DOI: 10.1007/s10198-017-0894-6
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    References listed on IDEAS

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    1. Tarricone, Rosanna, 2006. "Cost-of-illness analysis: What room in health economics?," Health Policy, Elsevier, vol. 77(1), pages 51-63, June.
    2. Jenny Berg & P. Lindgren & Sten Fredrikson & Gisela Kobelt, 2006. "Costs and quality of life of multiple sclerosis in Sweden," The European Journal of Health Economics, Springer;Deutsche Gesellschaft für Gesundheitsökonomie (DGGÖ), vol. 7(2), pages 75-85, July.
    3. Gisela Kobelt, 2006. "Costs and quality of life for patients with multiple sclerosis in Belgium," The European Journal of Health Economics, Springer;Deutsche Gesellschaft für Gesundheitsökonomie (DGGÖ), vol. 7(02), pages 24-33, July.
    4. Jenny Berg & P. Lindgren & Sten Fredrikson & Gisela Kobelt, 2006. "Costs and quality of life of multiple sclerosis in Sweden," The European Journal of Health Economics, Springer;Deutsche Gesellschaft für Gesundheitsökonomie (DGGÖ), vol. 7(02), pages 75-85, July.
    5. Johannesson, Magnus & Karlsson, Goran, 1997. "The friction cost method: A comment," Journal of Health Economics, Elsevier, vol. 16(2), pages 249-255, April.
    6. Koopmanschap, Marc A. & Rutten, Frans F. H. & van Ineveld, B. Martin & van Roijen, Leona, 1995. "The friction cost method for measuring indirect costs of disease," Journal of Health Economics, Elsevier, vol. 14(2), pages 171-189, June.
    7. Hartunian, N.S. & Smart, C.N. & Thompson, M.S., 1980. "The incidence and economic costs of cancer, motor vehicle injuries, coronary heart disease, and stroke: A comparative analysis," American Journal of Public Health, American Public Health Association, vol. 70(12), pages 1249-1260.
    8. Gisela Kobelt, 2006. "Costs and quality of life for patients with multiple sclerosis in Belgium," The European Journal of Health Economics, Springer;Deutsche Gesellschaft für Gesundheitsökonomie (DGGÖ), vol. 7(2), pages 24-33, July.
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    More about this item

    Keywords

    Multiple sclerosis; Cost of Illness; Registries; Third-party payers; Socioeconomic factors; Sick leave;
    All these keywords.

    JEL classification:

    • I14 - Health, Education, and Welfare - - Health - - - Health and Inequality
    • I18 - Health, Education, and Welfare - - Health - - - Government Policy; Regulation; Public Health
    • H51 - Public Economics - - National Government Expenditures and Related Policies - - - Government Expenditures and Health
    • H55 - Public Economics - - National Government Expenditures and Related Policies - - - Social Security and Public Pensions

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