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Who benefits from SMEs’ radical innovations?—empirical evidence from German biotechnology

Author

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  • Mariia Shkolnykova

    (University of Bremen)

  • Muhamed Kudic

    (University of Siegen)

Abstract

We analyze transfer channels of radical innovations launched by small and medium-sized firms (SMEs) using an ego network approach. Based on a unique longitudinal dataset covering the observation period 1996–2016, we identify and trace back radical innovations of SMEs in German Biotech in order to analyze the extent to which SMEs themselves—or eventually also other organizations in their direct cooperation surrounding—benefit from radical innovations in terms of subsequent innovation performance. Results from negative binomial panel regressions indicate that direct cooperation partners of radical innovators show higher innovative performance than partners of the control group, i.e., statistical twin firms without radical innovations. Our results confirm that radical innovations initiate a positive impulse for innovation through direct cooperative relationships. Interestingly, geographical proximity does not play a role, and especially technologically different partners benefit from direct cooperation with radical innovators. Plain English Summary Radical innovations are rare but have a great importance for the economy. Our study shows that not only radically innovating biotech SMEs themselves but also various types of directly linked cooperation partners benefit significantly. We investigate whether directly linked cooperation partners of radically innovating firms benefit from knowledge spillover transferred through formal cooperation. A radical innovation represents a novel and often complex combination of already existing knowledge. Thus, knowledge transfer process differs for radical and non-radical innovations. Project-based formal cooperation can support the transfer of radical knowledge. In this context geographical and technological factors matter. Using the example of German small and medium-sized biotechnology firms, we show that collaboration with radical firms is positively related to innovation performance of directly linked project partners. Interestingly, this effect is higher for partners located in other regions as well as for technologically distant partners. Our study extends the research on knowledge transfer by emphasizing the role of formal collaboration projects, especially in knowledge intensive high-tech industries.

Suggested Citation

  • Mariia Shkolnykova & Muhamed Kudic, 2022. "Who benefits from SMEs’ radical innovations?—empirical evidence from German biotechnology," Small Business Economics, Springer, vol. 58(2), pages 1157-1185, February.
  • Handle: RePEc:kap:sbusec:v:58:y:2022:i:2:d:10.1007_s11187-021-00464-x
    DOI: 10.1007/s11187-021-00464-x
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    as
    1. Joel A. C. Baum & Tony Calabrese & Brian S. Silverman, 2000. "Don't go it alone: alliance network composition and startups' performance in Canadian biotechnology," Strategic Management Journal, Wiley Blackwell, vol. 21(3), pages 267-294, March.
    2. Antonio Capaldo, 2007. "Network structure and innovation: The leveraging of a dual network as a distinctive relational capability," Strategic Management Journal, Wiley Blackwell, vol. 28(6), pages 585-608, June.
    3. Werner H. Hoffmann, 2007. "Strategies for managing a portfolio of alliances," Strategic Management Journal, Wiley Blackwell, vol. 28(8), pages 827-856, August.
    4. Adam B. Jaffe & Manuel Trajtenberg & Rebecca Henderson, 1993. "Geographic Localization of Knowledge Spillovers as Evidenced by Patent Citations," The Quarterly Journal of Economics, Oxford University Press, vol. 108(3), pages 577-598.
    5. Bernard L. Simonin, 1999. "Ambiguity and the process of knowledge transfer in strategic alliances," Strategic Management Journal, Wiley Blackwell, vol. 20(7), pages 595-623, July.
    6. Lionel Nesta & Ludovic Dibiaggio, 2003. "Technology Strategy and Knowledge Dynamics: The Case of Biotech¹," Industry and Innovation, Taylor & Francis Journals, vol. 10(3), pages 331-349.
    7. Tether, Bruce S., 2002. "Who co-operates for innovation, and why: An empirical analysis," Research Policy, Elsevier, vol. 31(6), pages 947-967, August.
    8. Autio, Erkko & Kenney, Martin & Mustar, Philippe & Siegel, Don & Wright, Mike, 2014. "Entrepreneurial innovation: The importance of context," Research Policy, Elsevier, vol. 43(7), pages 1097-1108.
    9. Freeman, C., 1991. "Networks of innovators: A synthesis of research issues," Research Policy, Elsevier, vol. 20(5), pages 499-514, October.
    10. Richard P. Nelson & Giovanni Dosi & Constance Helfat & Andreas Pyka & Pier-Paolo Saviotti & Keun Lee & Kurt Dopfer & Franco Malerba & Sidney Winter, 2018. "Modern evolutionary economics: an overview," Post-Print hal-02097506, HAL.
    11. Lisa De Propris, 2000. "Innovation And Inter-Firm Co-Operation: The Case Of The West Midlands," Economics of Innovation and New Technology, Taylor & Francis Journals, vol. 9(5), pages 421-446.
    12. Ayda Eraydin & Bilge Armatli-Köroğlu, 2005. "Innovation, networking and the new industrial clusters: the characteristics of networks and local innovation capabilities in the Turkish industrial clusters," Entrepreneurship & Regional Development, Taylor & Francis Journals, vol. 17(4), pages 237-266, July.
    13. Breschi, Stefano & Lissoni, Francesco, 2001. "Knowledge Spillovers and Local Innovation Systems: A Critical Survey," Industrial and Corporate Change, Oxford University Press, vol. 10(4), pages 975-1005, December.
    14. Paul Almeida & Bruce Kogut, 1999. "Localization of Knowledge and the Mobility of Engineers in Regional Networks," Management Science, INFORMS, vol. 45(7), pages 905-917, July.
    15. Maskell, Peter & Malmberg, Anders, 1999. "Localised Learning and Industrial Competitiveness," Cambridge Journal of Economics, Oxford University Press, vol. 23(2), pages 167-185, March.
    16. Vikas A. Aggarwal & David H. Hsu, 2014. "Entrepreneurial Exits and Innovation," Management Science, INFORMS, vol. 60(4), pages 867-887, April.
    17. Peter J. Lane & Michael Lubatkin, 1998. "Relative absorptive capacity and interorganizational learning," Post-Print hal-02311860, HAL.
    18. Nooteboom, Bart & Van Haverbeke, Wim & Duysters, Geert & Gilsing, Victor & van den Oord, Ad, 2007. "Optimal cognitive distance and absorptive capacity," Research Policy, Elsevier, vol. 36(7), pages 1016-1034, September.
    19. Scott Shane, 2001. "Technological Opportunities and New Firm Creation," Management Science, INFORMS, vol. 47(2), pages 205-220, February.
    20. Ulrich Witt, 2008. "What is specific about evolutionary economics?," Journal of Evolutionary Economics, Springer, vol. 18(5), pages 547-575, October.
    21. Gilbert, Brett Anitra & McDougall, Patricia P. & Audretsch, David B., 2008. "Clusters, knowledge spillovers and new venture performance: An empirical examination," Journal of Business Venturing, Elsevier, vol. 23(4), pages 405-422, July.
    22. Riitta Katila, 2000. "Using patent data to measure innovation performance," International Journal of Business Performance Management, Inderscience Enterprises Ltd, vol. 2(1/2/3), pages 180-193.
    23. Andrea Caragliu & Peter Nijkamp, 2016. "Space and knowledge spillovers in European regions: the impact of different forms of proximity on spatial knowledge diffusion," Journal of Economic Geography, Oxford University Press, vol. 16(3), pages 749-774.
    24. Muhamed Kudic, 2015. "Innovation Networks in the German Laser Industry," Economic Complexity and Evolution, Springer, edition 127, number 978-3-319-07935-6, June.
    25. Peter Kennedy, 2003. "A Guide to Econometrics, 5th Edition," MIT Press Books, The MIT Press, edition 5, volume 1, number 026261183x, December.
    26. Stefano Breschi & Francesco Lissoni, 2003. "Mobility and Social Networks: Localised Knowledge Spillovers Revisited," KITeS Working Papers 142, KITeS, Centre for Knowledge, Internationalization and Technology Studies, Universita' Bocconi, Milano, Italy, revised Mar 2003.
    27. Lee Fleming, 2001. "Recombinant Uncertainty in Technological Search," Management Science, INFORMS, vol. 47(1), pages 117-132, January.
    28. Malerba, Franco, 2002. "Sectoral systems of innovation and production," Research Policy, Elsevier, vol. 31(2), pages 247-264, February.
    29. Dovev Lavie & Stewart R. Miller, 2008. "Alliance Portfolio Internationalization and Firm Performance," Organization Science, INFORMS, vol. 19(4), pages 623-646, August.
    30. Nils Grashof & Kolja Hesse & Dirk Fornahl, 2019. "Radical or not? The role of clusters in the emergence of radical innovations," European Planning Studies, Taylor & Francis Journals, vol. 27(10), pages 1904-1923, October.
    31. Carlsson, Bo & Jacobsson, Staffan & Holmen, Magnus & Rickne, Annika, 2002. "Innovation systems: analytical and methodological issues," Research Policy, Elsevier, vol. 31(2), pages 233-245, February.
    32. Verhoeven, Dennis & Bakker, Jurriën & Veugelers, Reinhilde, 2016. "Measuring technological novelty with patent-based indicators," Research Policy, Elsevier, vol. 45(3), pages 707-723.
    33. Najib Harabi, 2002. "The Impact of Vertical R&D Cooperation on Firm Innovation: An Empirical Investigation," Economics of Innovation and New Technology, Taylor & Francis Journals, vol. 11(2), pages 93-108.
    34. repec:adr:anecst:y:2005:i:79-80:p:08 is not listed on IDEAS
    35. Dirk Fornahl & Tom Broekel & Ron Boschma, 2011. "What drives patent performance of German biotech firms? The impact of R&D subsidies, knowledge networks and their location," Papers in Regional Science, Wiley Blackwell, vol. 90(2), pages 395-418, June.
    36. Zucker, Lynne G & Darby, Michael R & Armstrong, Jeff, 1998. "Geographically Localized Knowledge: Spillovers or Markets?," Economic Inquiry, Western Economic Association International, vol. 36(1), pages 65-86, January.
    37. Jeffrey H. Dyer & Kentaro Nobeoka, 2000. "Creating and managing a high‐performance knowledge‐sharing network: the Toyota case," Strategic Management Journal, Wiley Blackwell, vol. 21(3), pages 345-367, March.
    38. Julie M. Hite & William S. Hesterly, 2001. "The evolution of firm networks: from emergence to early growth of the firm," Strategic Management Journal, Wiley Blackwell, vol. 22(3), pages 275-286, March.
    39. Nelson, Richard R & Winter, Sidney G, 1974. "Neoclassical vs. Evolutionary Theories of Economic Growth: Critique and Prospectus," Economic Journal, Royal Economic Society, vol. 84(336), pages 886-905, December.
    40. Robert M. Grant & Charles Baden‐Fuller, 2004. "A Knowledge Accessing Theory of Strategic Alliances," Journal of Management Studies, Wiley Blackwell, vol. 41(1), pages 61-84, January.
    41. Tom Broekel & Ron Boschma, 2012. "Knowledge networks in the Dutch aviation industry: the proximity paradox," Journal of Economic Geography, Oxford University Press, vol. 12(2), pages 409-433, March.
    42. Dahlin, Kristina B. & Behrens, Dean M., 2005. "When is an invention really radical?: Defining and measuring technological radicalness," Research Policy, Elsevier, vol. 34(5), pages 717-737, June.
    43. Stefano Breschi & Francesco Lissoni, 2010. ""Cross-Firm" Inventors and Social Networks: Localized Knowledge Spillovers Revisited," NBER Chapters, in: Contributions in Memory of Zvi Griliches, pages 189-209, National Bureau of Economic Research, Inc.
    44. Thomas Scherngell & Michael J. Barber, 2009. "Spatial interaction modelling of cross‐region R&D collaborations: empirical evidence from the 5th EU framework programme," Papers in Regional Science, Wiley Blackwell, vol. 88(3), pages 531-546, August.
    45. Malerba, Franco & Orsenigo, Luigi, 1997. "Technological Regimes and Sectoral Patterns of Innovative Activities," Industrial and Corporate Change, Oxford University Press and the Associazione ICC, vol. 6(1), pages 83-117.
    46. Stefano Breschi & Francesco Lissoni, 2009. "Mobility of skilled workers and co-invention networks: an anatomy of localized knowledge flows," Journal of Economic Geography, Oxford University Press, vol. 9(4), pages 439-468, July.
    47. Kristina Dahlin & Deans M. Behrens, 2005. "When is an invention really radical? Defining and measuring technological radicalness," Post-Print hal-00480416, HAL.
    48. Frans A. J. Van den Bosch & Henk W. Volberda & Michiel de Boer, 1999. "Coevolution of Firm Absorptive Capacity and Knowledge Environment: Organizational Forms and Combinative Capabilities," Organization Science, INFORMS, vol. 10(5), pages 551-568, October.
    49. Ron Boschma, 2005. "Proximity and Innovation: A Critical Assessment," Regional Studies, Taylor & Francis Journals, vol. 39(1), pages 61-74.
    50. Mark Freel & Richard Harrison, 2006. "Innovation and cooperation in the small firm sector: Evidence from 'Northern Britain'," Regional Studies, Taylor & Francis Journals, vol. 40(4), pages 289-305.
    51. Gay, Brigitte & Dousset, Bernard, 2005. "Innovation and network structural dynamics: Study of the alliance network of a major sector of the biotechnology industry," Research Policy, Elsevier, vol. 34(10), pages 1457-1475, December.
    52. Bart Nooteboom, 2000. "Learning by Interaction: Absorptive Capacity, Cognitive Distance and Governance," Journal of Management & Governance, Springer;Accademia Italiana di Economia Aziendale (AIDEA), vol. 4(1), pages 69-92, March.
    53. Peter J. Lane & Jane E. Salk & Marjorie A. Lyles, 2001. "Absorptive capacity, learning, and performance in international joint ventures," Strategic Management Journal, Wiley Blackwell, vol. 22(12), pages 1139-1161, December.
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