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A more accurate method for colocalisation analysis allowing for multiple causal variants

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  1. Sophie A. Riesmeijer & Zoha Kamali & Michael Ng & Dmitriy Drichel & Bram Piersma & Kerstin Becker & Thomas B. Layton & Jagdeep Nanchahal & Michael Nothnagel & Ahmad Vaez & Hans Christian Hennies & Pau, 2024. "A genome-wide association meta-analysis implicates Hedgehog and Notch signaling in Dupuytren’s disease," Nature Communications, Nature, vol. 15(1), pages 1-11, December.
  2. Wesley L Crouse & Gregory R Keele & Madeleine S Gastonguay & Gary A Churchill & William Valdar, 2022. "A Bayesian model selection approach to mediation analysis," PLOS Genetics, Public Library of Science, vol. 18(5), pages 1-33, May.
  3. Karl Smith-Byrne & Åsa Hedman & Marios Dimitriou & Trishna Desai & Alexandr V. Sokolov & Helgi B. Schioth & Mine Koprulu & Maik Pietzner & Claudia Langenberg & Joshua Atkins & Ricardo Cortez Penha & J, 2024. "Identifying therapeutic targets for cancer among 2074 circulating proteins and risk of nine cancers," Nature Communications, Nature, vol. 15(1), pages 1-11, December.
  4. Matthew T. Patrick & Qinmengge Li & Rachael Wasikowski & Nehal Mehta & Johann E. Gudjonsson & James T. Elder & Xiang Zhou & Lam C. Tsoi, 2022. "Shared genetic risk factors and causal association between psoriasis and coronary artery disease," Nature Communications, Nature, vol. 13(1), pages 1-12, December.
  5. Hanmin Guo & Alexander Eckehart Urban & Wing Hung Wong, 2024. "Prioritizing disease-related rare variants by integrating gene expression data," PLOS Genetics, Public Library of Science, vol. 20(9), pages 1-16, September.
  6. Valur Emilsson & Elias F. Gudmundsson & Thorarinn Jonmundsson & Brynjolfur G. Jonsson & Michael Twarog & Valborg Gudmundsdottir & Zhiguang Li & Nancy Finkel & Stephen Poor & Xin Liu & Robert Esterberg, 2022. "A proteogenomic signature of age-related macular degeneration in blood," Nature Communications, Nature, vol. 13(1), pages 1-15, December.
  7. Seyoun Byun & Jacqueline Shine & Philip Coryell & Nicole E. Kramer & Susan D’Costa & Eliza Thulson & Sylvie M. Parkus & Susan Chubinskaya & Richard F. Loeser & Brian O. Diekman & Douglas H. Phanstiel, 2025. "Response splicing quantitative trait loci in primary human chondrocytes identify putative osteoarthritis risk genes," Nature Communications, Nature, vol. 16(1), pages 1-17, December.
  8. Ruo-Han Hao & Tian-Pei Zhang & Feng Jiang & Jun-Hui Liu & Shan-Shan Dong & Meng Li & Yan Guo & Tie-Lin Yang, 2024. "Revealing brain cell-stratified causality through dissecting causal variants according to their cell-type-specific effects on gene expression," Nature Communications, Nature, vol. 15(1), pages 1-11, December.
  9. V. E. Jackson & Y. Wu & R. Bonelli & J. P. Owen & L. W. Scott & S. Farashi & Y. Kihara & M. L. Gantner & C. Egan & K. M. Williams & B. R. E. Ansell & A. Tufail & A. Y. Lee & M. Bahlo, 2025. "Multi-omic spatial effects on high-resolution AI-derived retinal thickness," Nature Communications, Nature, vol. 16(1), pages 1-19, December.
  10. Chengran Yang & Priyanka Gorijala & Jigyasha Timsina & Lihua Wang & Menghan Liu & Ciyang Wang & William Brock & Yueyao Wang & Fumihiko Urano & Yun Ju Sung & Carlos Cruchaga, 2025. "European and African ancestry-specific plasma protein-QTL and metabolite-QTL analyses identify ancestry-specific T2D effector proteins and metabolites," Nature Communications, Nature, vol. 16(1), pages 1-15, December.
  11. Laavanya Sankaranarayanan & Kelly J. Brewer & Shauna Morrow & Graham D. Johnson & Alejandro Barrera & Revathy Venukuttan & Ryan Sisk & Andrea Dunaif & Timothy E. Reddy, 2025. "Gene regulatory activity associated with polycystic ovary syndrome revealed DENND1A-dependent testosterone production," Nature Communications, Nature, vol. 16(1), pages 1-19, December.
  12. Linda Kachuri & Geno A. Guerra & Taishi Nakase & George A. Wendt & Helen M. Hansen & Annette M. Molinaro & Paige Bracci & Lucie McCoy & Terri Rice & John K. Wiencke & Jeanette E. Eckel-Passow & Robert, 2025. "Genetic predisposition to altered blood cell homeostasis is associated with glioma risk and survival," Nature Communications, Nature, vol. 16(1), pages 1-13, December.
  13. Yihe Yang & Noah Lorincz-Comi & Xiaofeng Zhu, 2025. "Uncovering causal gene-tissue pairs and variants through a multivariate TWAS controlling for infinitesimal effects," Nature Communications, Nature, vol. 16(1), pages 1-18, December.
  14. Amil M. Shah & Peder L. Myhre & Victoria Arthur & Pranav Dorbala & Humaira Rasheed & Leo F. Buckley & Brian Claggett & Guning Liu & Jianzhong Ma & Ngoc Quynh Nguyen & Kunihiro Matsushita & Chiadi Ndum, 2024. "Large scale plasma proteomics identifies novel proteins and protein networks associated with heart failure development," Nature Communications, Nature, vol. 15(1), pages 1-18, December.
  15. Anders Gummesson & Per Lundmark & Qiao Sen Chen & Elias Björnson & Koen F. Dekkers & Ulf Hammar & Martin Adiels & Yunzhang Wang & Therese Andersson & Göran Bergström & Carl-Johan Carlhäll & David Erli, 2025. "A genome-wide association study of imaging-defined atherosclerosis," Nature Communications, Nature, vol. 16(1), pages 1-12, December.
  16. Ichcha Manipur & Guillermo Reales & Jae Hoon Sul & Myung Kyun Shin & Simonne Longerich & Adrian Cortes & Chris Wallace, 2024. "CoPheScan: phenome-wide association studies accounting for linkage disequilibrium," Nature Communications, Nature, vol. 15(1), pages 1-13, December.
  17. Anna Gui & Anja Hollowell & Emilie M. Wigdor & Morgan J. Morgan & Laurie J. Hannigan & Elizabeth C. Corfield & Veronika Odintsova & Jouke-Jan Hottenga & Andrew Wong & René Pool & Harriet Cullen & Siân, 2025. "Genome-wide association meta-analysis of age at onset of walking in over 70,000 infants of European ancestry," Nature Human Behaviour, Nature, vol. 9(7), pages 1470-1487, July.
  18. Feng Jiang & Shou-Ye Hu & Wen Tian & Nai-Ning Wang & Ning Yang & Shan-Shan Dong & Hui-Miao Song & Da-Jin Zhang & Hui-Wu Gao & Chen Wang & Hao Wu & Chang-Yi He & Dong-Li Zhu & Xiao-Feng Chen & Yan Guo , 2024. "A landscape of gene expression regulation for synovium in arthritis," Nature Communications, Nature, vol. 15(1), pages 1-16, December.
  19. Shuai Yuan & Jie Chen & Xixin Ruan & Yuying Li & Sarah A. Abramowitz & Lijuan Wang & Fangyuan Jiang & Ying Xiong & Michael G. Levin & Benjamin F. Voight & Dipender Gill & Stephen Burgess & Agneta Åkes, 2025. "Cross-population GWAS and proteomics improve risk prediction and reveal mechanisms in atrial fibrillation," Nature Communications, Nature, vol. 16(1), pages 1-13, December.
  20. Bryan R. Gorman & Sun-Gou Ji & Michael Francis & Anoop K. Sendamarai & Yunling Shi & Poornima Devineni & Uma Saxena & Elizabeth Partan & Andrea K. DeVito & Jinyoung Byun & Younghun Han & Xiangjun Xiao, 2024. "Multi-ancestry GWAS meta-analyses of lung cancer reveal susceptibility loci and elucidate smoking-independent genetic risk," Nature Communications, Nature, vol. 15(1), pages 1-13, December.
  21. Adriaan Graaf & Robert Warmerdam & Chiara Auwerx & Urmo Võsa & Maria Carolina Borges & Lude Franke & Zoltán Kutalik, 2025. "MR-link-2: pleiotropy robust cis Mendelian randomization validated in three independent reference datasets of causality," Nature Communications, Nature, vol. 16(1), pages 1-19, December.
  22. Yingbo Huang & Yuting Shan & Weijie Zhang & Adam M. Lee & Feng Li & Barbara E. Stranger & R. Stephanie Huang, 2023. "Deciphering genetic causes for sex differences in human health through drug metabolism and transporter genes," Nature Communications, Nature, vol. 14(1), pages 1-15, December.
  23. Ying Chen & Panpan Liu & Aniko Sabo & Dongyin Guan, 2025. "Human genetic variation determines 24-hour rhythmic gene expression and disease risk," Nature Communications, Nature, vol. 16(1), pages 1-14, December.
  24. Douglas P. Loesch & Manik Garg & Dorota Matelska & Dimitrios Vitsios & Xiao Jiang & Scott C. Ritchie & Benjamin B. Sun & Heiko Runz & Christopher D. Whelan & Rury R. Holman & Robert J. Mentz & Filipe , 2025. "Identification of plasma proteomic markers underlying polygenic risk of type 2 diabetes and related comorbidities," Nature Communications, Nature, vol. 16(1), pages 1-16, December.
  25. Lucas A. Mavromatis & Daniel B. Rosoff & Andrew S. Bell & Jeesun Jung & Josephin Wagner & Falk W. Lohoff, 2023. "Multi-omic underpinnings of epigenetic aging and human longevity," Nature Communications, Nature, vol. 14(1), pages 1-15, December.
  26. Yon Ho Jee & Ying Wang & Keum Ji Jung & Ji-Young Lee & Heejin Kimm & Rui Duan & Alkes L. Price & Alicia R. Martin & Peter Kraft, 2025. "Genome-wide association studies in a large Korean cohort identify quantitative trait loci for 36 traits and illuminate their genetic architectures," Nature Communications, Nature, vol. 16(1), pages 1-13, December.
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