Neurotoxic reactive astrocytes are induced by activated microglia

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3. Kaya J. E. Matson & Daniel E. Russ & Claudia Kathe & Isabelle Hua & Dragan Maric & Yi Ding & Jonathan Krynitsky & Randall Pursley & Anupama Sathyamurthy & Jordan W. Squair & Boaz P. Levi & Gregoire Co, 2022. "Single cell atlas of spinal cord injury in mice reveals a pro-regenerative signature in spinocerebellar neurons," Nature Communications, Nature, vol. 13(1), pages 1-16, December.
4. Hyun-Sik Yang & Ling Teng & Daniel Kang & Vilas Menon & Tian Ge & Hilary K. Finucane & Aaron P. Schultz & Michael Properzi & Hans-Ulrich Klein & Lori B. Chibnik & Julie A. Schneider & David A. Bennett, 2023. "Cell-type-specific Alzheimer’s disease polygenic risk scores are associated with distinct disease processes in Alzheimer’s disease," Nature Communications, Nature, vol. 14(1), pages 1-13, December.
5. Flavio Pisani & Valerio Pisani & Francesca Arcangeli & Alice Harding & Simarjit Kaur Singhrao, 2023. "Treponema denticola Has the Potential to Cause Neurodegeneration in the Midbrain via the Periodontal Route of Infection—Narrative Review," IJERPH, MDPI, vol. 20(11), pages 1-16, June.
6. David J. Whiteside & Negin Holland & Kamen A. Tsvetanov & Elijah Mak & Maura Malpetti & George Savulich & P. Simon Jones & Michelle Naessens & Matthew A. Rouse & Tim D. Fryer & Young T. Hong & Frankli, 2023. "Synaptic density affects clinical severity via network dysfunction in syndromes associated with frontotemporal lobar degeneration," Nature Communications, Nature, vol. 14(1), pages 1-13, December.
7. Christina Koupourtidou & Veronika Schwarz & Hananeh Aliee & Simon Frerich & Judith Fischer-Sternjak & Riccardo Bocchi & Tatiana Simon-Ebert & Xianshu Bai & Swetlana Sirko & Frank Kirchhoff & Martin Di, 2024. "Shared inflammatory glial cell signature after stab wound injury, revealed by spatial, temporal, and cell-type-specific profiling of the murine cerebral cortex," Nature Communications, Nature, vol. 15(1), pages 1-22, December.
8. Xiaojing Shi & Longlong Luo & Jixian Wang & Hui Shen & Yongfang Li & Muyassar Mamtilahun & Chang Liu & Rubing Shi & Joon-Hyuk Lee & Hengli Tian & Zhijun Zhang & Yongting Wang & Won-Suk Chung & Yaohui , 2021. "Stroke subtype-dependent synapse elimination by reactive gliosis in mice," Nature Communications, Nature, vol. 12(1), pages 1-19, December.
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10. Yuanning Zheng & Francisco Carrillo-Perez & Marija Pizurica & Dieter Henrik Heiland & Olivier Gevaert, 2023. "Spatial cellular architecture predicts prognosis in glioblastoma," Nature Communications, Nature, vol. 14(1), pages 1-16, December.
11. Thomas Garton & Matthew D. Smith & Ajay Kesharwani & Marjan Gharagozloo & Sungtaek Oh & Chan-Hyun Na & Martina Absinta & Daniel S. Reich & Donald J. Zack & Peter A. Calabresi, 2025. "Myeloid lineage C3 induces reactive gliosis and neuronal stress during CNS inflammation," Nature Communications, Nature, vol. 16(1), pages 1-21, December.
12. Qilin Guo & Davide Gobbo & Na Zhao & Hong Zhang & Nana-Oye Awuku & Qing Liu & Li-Pao Fang & Tanja M. Gampfer & Markus R. Meyer & Renping Zhao & Xianshu Bai & Shan Bian & Anja Scheller & Frank Kirchhof, 2024. "Adenosine triggers early astrocyte reactivity that provokes microglial responses and drives the pathogenesis of sepsis-associated encephalopathy in mice," Nature Communications, Nature, vol. 15(1), pages 1-19, December.
13. Fan Li & Jazlyn Gallego & Natasha N. Tirko & Jenna Greaser & Derek Bashe & Rudra Patel & Eric Shaker & Grace E. Valkenburg & Alanoud S. Alsubhi & Steven Wellman & Vanshika Singh & Camila Garcia Padill, 2024. "Low-intensity pulsed ultrasound stimulation (LIPUS) modulates microglial activation following intracortical microelectrode implantation," Nature Communications, Nature, vol. 15(1), pages 1-21, December.
14. Levi Hijfte & Marjolein Geurts & Iris Heer & Santoesha A. Ghisai & Hayri E. Balcioglu & Youri Hoogstrate & Wies R. Vallentgoed & Rania Head & Rosa Luning & Thierry Bosch & Bart Westerman & Pieter Wess, 2025. "Gemistocytic tumor cells programmed for glial scarring characterize T cell confinement in IDH-mutant astrocytoma," Nature Communications, Nature, vol. 16(1), pages 1-16, December.
15. Floriane Bretheau & Adrian Castellanos-Molina & Dominic Bélanger & Maxime Kusik & Benoit Mailhot & Ana Boisvert & Nicolas Vallières & Martine Lessard & Matthias Gunzer & Xiaoyu Liu & Éric Boilard & Ni, 2022. "The alarmin interleukin-1α triggers secondary degeneration through reactive astrocytes and endothelium after spinal cord injury," Nature Communications, Nature, vol. 13(1), pages 1-22, December.
16. Ziyu Wan & Tao Ma, 2025. "The impact of apolipoprotein E, type ∊4 allele on Alzheimer’s disease pathological biomarkers: a comprehensive post-mortem pilot-analysis," PLOS ONE, Public Library of Science, vol. 20(2), pages 1-20, February.
17. A. de Rus Jacquet & M. Alpaugh & H. L. Denis & J. L. Tancredi & M. Boutin & J. Decaestecker & C. Beauparlant & L. Herrmann & M. Saint-Pierre & M. Parent & A. Droit & S. Breton & F. Cicchetti, 2023. "The contribution of inflammatory astrocytes to BBB impairments in a brain-chip model of Parkinson’s disease," Nature Communications, Nature, vol. 14(1), pages 1-21, December.
18. Noah R. Johnson & Peng Yuan & Erika Castillo & T. Peter Lopez & Weizhou Yue & Annalise Bond & Brianna M. Rivera & Miranda C. Sullivan & Masakazu Hirouchi & Kurt Giles & Atsushi Aoyagi & Carlo Condello, 2023. "CSF1R inhibitors induce a sex-specific resilient microglial phenotype and functional rescue in a tauopathy mouse model," Nature Communications, Nature, vol. 14(1), pages 1-23, December.
19. Hyosung Kim & Kun Leng & Jinhee Park & Alexander G. Sorets & Suil Kim & Alena Shostak & Rebecca J. Embalabala & Kate Mlouk & Ketaki A. Katdare & Indigo V. L. Rose & Sarah M. Sturgeon & Emma H. Neal & , 2022. "Reactive astrocytes transduce inflammation in a blood-brain barrier model through a TNF-STAT3 signaling axis and secretion of alpha 1-antichymotrypsin," Nature Communications, Nature, vol. 13(1), pages 1-18, December.
20. Faith H. Brennan & Yang Li & Cankun Wang & Anjun Ma & Qi Guo & Yi Li & Nicole Pukos & Warren A. Campbell & Kristina G. Witcher & Zhen Guan & Kristina A. Kigerl & Jodie C. E. Hall & Jonathan P. Godbout, 2022. "Microglia coordinate cellular interactions during spinal cord repair in mice," Nature Communications, Nature, vol. 13(1), pages 1-20, December.
21. Nicole D. Schartz & Heidi Y. Liang & Klebea Carvalho & Shu-Hui Chu & Adrian Mendoza-Arvilla & Tiffany J. Petrisko & Angela Gomez-Arboledas & Ali Mortazavi & Andrea J. Tenner, 2024. "C5aR1 antagonism suppresses inflammatory glial responses and alters cellular signaling in an Alzheimer’s disease mouse model," Nature Communications, Nature, vol. 15(1), pages 1-16, December.
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24. Michaela M. Novakovic & Kirill S. Korshunov & Rogan A. Grant & Megan E. Martin & Hiam A. Valencia & G. R. Scott Budinger & Jelena Radulovic & Murali Prakriya, 2023. "Astrocyte reactivity and inflammation-induced depression-like behaviors are regulated by Orai1 calcium channels," Nature Communications, Nature, vol. 14(1), pages 1-20, December.
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