Genomic analyses identify molecular subtypes of pancreatic cancer

Citations

Cited by:

1. Shivan Sivakumar & Ashwin Jainarayanan & Edward Arbe-Barnes & Piyush Kumar Sharma & Maire Ni Leathlobhair & Sakina Amin & David J. Reiss & Lara Heij & Samarth Hegde & Assaf Magen & Felicia Tucci & Bo , 2025. "Distinct immune cell infiltration patterns in pancreatic ductal adenocarcinoma (PDAC) exhibit divergent immune cell selection and immunosuppressive mechanisms," Nature Communications, Nature, vol. 16(1), pages 1-20, December.
2. Jonathan J. Swietlik & Stefanie Bärthel & Chiara Falcomatà & Diana Fink & Ankit Sinha & Jingyuan Cheng & Stefan Ebner & Peter Landgraf & Daniela C. Dieterich & Henrik Daub & Dieter Saur & Felix Meissn, 2023. "Cell-selective proteomics segregates pancreatic cancer subtypes by extracellular proteins in tumors and circulation," Nature Communications, Nature, vol. 14(1), pages 1-17, December.
3. Lukas Klein & Mengyu Tu & Niklas Krebs & Laura Urbach & Daniela Grimm & Muhammad Umair Latif & Frederike Penz & Anna Blandau & Xueyan Wu & Rebecca Diya Samuel & Stefan Küffer & Florian Wegwitz & Natha, 2025. "Spatial tumor immune heterogeneity facilitates subtype co-existence and therapy response in pancreatic cancer," Nature Communications, Nature, vol. 16(1), pages 1-19, December.
4. S. Randriamanantsoa & A. Papargyriou & H. C. Maurer & K. Peschke & M. Schuster & G. Zecchin & K. Steiger & R. Öllinger & D. Saur & C. Scheel & R. Rad & E. Hannezo & M. Reichert & A. R. Bausch, 2022. "Spatiotemporal dynamics of self-organized branching in pancreas-derived organoids," Nature Communications, Nature, vol. 13(1), pages 1-15, December.
5. Teklab Gebregiworgis & Yoshihito Kano & Jonathan St-Germain & Nikolina Radulovich & Molly L. Udaskin & Ahmet Mentes & Richard Huang & Betty P. K. Poon & Wenguang He & Ivette Valencia-Sama & Claire M. , 2021. "The Q61H mutation decouples KRAS from upstream regulation and renders cancer cells resistant to SHP2 inhibitors," Nature Communications, Nature, vol. 12(1), pages 1-15, December.
6. Hongjuan Yao & Wenping Song & Rui Cao & Cheng Ye & Li Zhang & Hebing Chen & Junting Wang & Yuchen Shi & Rui Li & Yi Li & Xiujun Liu & Xiaofei Zhou & Rongguang Shao & Liang Li, 2022. "An EGFR/HER2-targeted conjugate sensitizes gemcitabine-sensitive and resistant pancreatic cancer through different SMAD4-mediated mechanisms," Nature Communications, Nature, vol. 13(1), pages 1-24, December.
7. Xiaohan Shi & Yunguang Li & Qiuyue Yuan & Shijie Tang & Shiwei Guo & Yehan Zhang & Juan He & Xiaoyu Zhang & Ming Han & Zhuang Liu & Yiqin Zhu & Suizhi Gao & Huan Wang & Xiongfei Xu & Kailian Zheng & W, 2022. "Integrated profiling of human pancreatic cancer organoids reveals chromatin accessibility features associated with drug sensitivity," Nature Communications, Nature, vol. 13(1), pages 1-16, December.
8. Charlie Saillard & Flore Delecourt & Benoit Schmauch & Olivier Moindrot & Magali Svrcek & Armelle Bardier-Dupas & Jean Francois Emile & Mira Ayadi & Vinciane Rebours & Louis de Mestier & Pascal Hammel, 2023. "Pacpaint: a histology-based deep learning model uncovers the extensive intratumor molecular heterogeneity of pancreatic adenocarcinoma," Nature Communications, Nature, vol. 14(1), pages 1-12, December.
9. Sebastien Martinez & Shifei Wu & Michael Geuenich & Ahmad Malik & Ramona Weber & Tristan Woo & Amy Zhang & Gun Ho Jang & Dzana Dervovic & Khalid N. Al-Zahrani & Ricky Tsai & Nassima Fodil & Philippe G, 2024. "In vivo CRISPR screens reveal SCAF1 and USP15 as drivers of pancreatic cancer," Nature Communications, Nature, vol. 15(1), pages 1-15, December.
10. Xiaoyi Yin & Hui Shen & Huan Wang & Qingchen Wang & Shan Zhang & Chunming Zhang & Qi Jia & Shiwei Guo & Xiongfei Xu & Wenhui Zhang & Bo Li & Xiaohan Shi & Suizhi Gao & Meilong Shi & Xuenan Zhao & Shen, 2025. "Pathogenic germline variants in Chinese pancreatic adenocarcinoma patients," Nature Communications, Nature, vol. 16(1), pages 1-20, December.
11. Siqi Li & Kun Li & Kang Wang & Haoyuan Yu & Xiangyang Wang & Mengchen Shi & Zhixing Liang & Zhou Yang & Yongwei Hu & Yang Li & Wei Liu & Hua Li & Shuqun Cheng & Linsen Ye & Yang Yang, 2023. "Low-dose radiotherapy combined with dual PD-L1 and VEGFA blockade elicits antitumor response in hepatocellular carcinoma mediated by activated intratumoral CD8+ exhausted-like T cells," Nature Communications, Nature, vol. 14(1), pages 1-21, December.
12. Yalan Deng & Xianghou Xia & Yang Zhao & Zilong Zhao & Consuelo Martinez & Wenjuan Yin & Jun Yao & Qinglei Hang & Weiche Wu & Jie Zhang & Yang Yu & Weiya Xia & Fan Yao & Di Zhao & Yutong Sun & Haoqiang, 2021. "Glucocorticoid receptor regulates PD-L1 and MHC-I in pancreatic cancer cells to promote immune evasion and immunotherapy resistance," Nature Communications, Nature, vol. 12(1), pages 1-16, December.
13. Abdallah Gaballa & Anneli Gebhardt-Wolf & Bastian Krenz & Greta Mattavelli & Mara John & Giacomo Cossa & Silvia Andreani & Christina Schülein-Völk & Francisco Montesinos & Raphael Vidal & Carolin Kast, 2024. "PAF1c links S-phase progression to immune evasion and MYC function in pancreatic carcinoma," Nature Communications, Nature, vol. 15(1), pages 1-18, December.
14. Abdur Rahman M. A. Basher & Caleb Hallinan & Kwonmoo Lee, 2025. "Heterogeneity-preserving discriminative feature selection for disease-specific subtype discovery," Nature Communications, Nature, vol. 16(1), pages 1-25, December.
15. Gregor Werba & Daniel Weissinger & Emily A. Kawaler & Ende Zhao & Despoina Kalfakakou & Surajit Dhara & Lidong Wang & Heather B. Lim & Grace Oh & Xiaohong Jing & Nina Beri & Lauren Khanna & Tamas Gond, 2023. "Single-cell RNA sequencing reveals the effects of chemotherapy on human pancreatic adenocarcinoma and its tumor microenvironment," Nature Communications, Nature, vol. 14(1), pages 1-16, December.
16. Peter Bailey & Rachel A. Ridgway & Patrizia Cammareri & Mairi Treanor-Taylor & Ulla-Maja Bailey & Christina Schoenherr & Max Bone & Daniel Schreyer & Karin Purdie & Jason Thomson & William Rickaby & R, 2023. "Driver gene combinations dictate cutaneous squamous cell carcinoma disease continuum progression," Nature Communications, Nature, vol. 14(1), pages 1-14, December.
17. Marie-Eve Wedge & Victoria A. Jennings & Mathieu J. F. Crupi & Joanna Poutou & Taylor Jamieson & Adrian Pelin & Giuseppe Pugliese & Christiano Tanese Souza & Julia Petryk & Brian J. Laight & Meaghan B, 2022. "Virally programmed extracellular vesicles sensitize cancer cells to oncolytic virus and small molecule therapy," Nature Communications, Nature, vol. 13(1), pages 1-16, December.
18. Zhaoqi Shu & Minghe Fan & Bo Tu & Zhiheng Tang & Haojie Wang & Haimeng Li & Hengchao Li & Meng Yuan & Jingru Bai & Sihan Huo & Lina Wang & Wei-Guo Zhu & Wei Wang & Xiaoyun Liu & Shaokun Shu & Ying Zha, 2023. "The Lin28b/Wnt5a axis drives pancreas cancer through crosstalk between cancer associated fibroblasts and tumor epithelium," Nature Communications, Nature, vol. 14(1), pages 1-18, December.
19. Yanfen Zheng & Xingyang Li & Shuang Deng & Hongzhe Zhao & Ying Ye & Shaoping Zhang & Xudong Huang & Ruihong Bai & Lisha Zhuang & Quanbo Zhou & Mei Li & Jiachun Su & Rui Li & Xiaoqiong Bao & Lingxing Z, 2023. "CSTF2 mediated mRNA N6-methyladenosine modification drives pancreatic ductal adenocarcinoma m6A subtypes," Nature Communications, Nature, vol. 14(1), pages 1-17, December.
20. James T. Topham & Erica S. Tsang & Joanna M. Karasinska & Andrew Metcalfe & Hassan Ali & Steve E. Kalloger & Veronika Csizmok & Laura M. Williamson & Emma Titmuss & Karina Nielsen & Gian Luca Negri & , 2022. "Integrative analysis of KRAS wildtype metastatic pancreatic ductal adenocarcinoma reveals mutation and expression-based similarities to cholangiocarcinoma," Nature Communications, Nature, vol. 13(1), pages 1-13, December.
21. John Fadul & Teresa Zulueta-Coarasa & Gloria M. Slattum & Nadja M. Redd & Mauricio Franco Jin & Michael J. Redd & Stephan Daetwyler & Danielle Hedeen & Jan Huisken & Jody Rosenblatt, 2021. "KRas-transformed epithelia cells invade and partially dedifferentiate by basal cell extrusion," Nature Communications, Nature, vol. 12(1), pages 1-9, December.
22. Shigekazu Murakami & Shannon M. White & Alec T. McIntosh & Chan D. K. Nguyen & Chunling Yi, 2023. "Spontaneously evolved progenitor niches escape Yap oncogene addiction in advanced pancreatic ductal adenocarcinomas," Nature Communications, Nature, vol. 14(1), pages 1-20, December.
23. Bárbara Andrade Barbosa & Saskia D. Asten & Ji Won Oh & Arantza Farina-Sarasqueta & Joanne Verheij & Frederike Dijk & Hanneke W. M. Laarhoven & Bauke Ylstra & Juan J. Garcia Vallejo & Mark A. Wiel & Y, 2021. "Bayesian log-normal deconvolution for enhanced in silico microdissection of bulk gene expression data," Nature Communications, Nature, vol. 12(1), pages 1-13, December.
24. Michelle Maurin & Mohammadreza Ranjouri & Cristina Megino-Luque & Justin Y. Newberg & Dongliang Du & Katelyn Martin & Robert E. Miner & Mollie S. Prater & Dave Keng Boon Wee & Barbara Centeno & Shondr, 2023. "RBFOX2 deregulation promotes pancreatic cancer progression and metastasis through alternative splicing," Nature Communications, Nature, vol. 14(1), pages 1-18, December.
25. Lisa Veghini & Davide Pasini & Rui Fang & Pietro Delfino & Dea Filippini & Christian Neander & Caterina Vicentini & Elena Fiorini & Francesca Lupo & Sabrina L. D’Agosto & Carmine Carbone & Antonio Ago, 2024. "Differential activity of MAPK signalling defines fibroblast subtypes in pancreatic cancer," Nature Communications, Nature, vol. 15(1), pages 1-20, December.
26. Meilin Xue & Youwei Zhu & Yongsheng Jiang & Lijie Han & Minmin Shi & Rui Su & Liwen Wang & Cheng Xiong & Chaofu Wang & Ting Wang & Shijie Deng & Dong Wu & Yizhi Cao & Lei Dong & Fan Bai & Shulin Zhao , 2023. "Schwann cells regulate tumor cells and cancer-associated fibroblasts in the pancreatic ductal adenocarcinoma microenvironment," Nature Communications, Nature, vol. 14(1), pages 1-18, December.