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Predictive correlates of response to the anti-PD-L1 antibody MPDL3280A in cancer patients

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Cited by:

  1. Matthew T. Campbell & Surena F. Matin & Alda L. Tam & Rahul A. Sheth & Kamran Ahrar & Rebecca S. Tidwell & Priya Rao & Jose A. Karam & Christopher G. Wood & Nizar M. Tannir & Eric Jonasch & Jianjun Ga, 2021. "Pilot study of Tremelimumab with and without cryoablation in patients with metastatic renal cell carcinoma," Nature Communications, Nature, vol. 12(1), pages 1-12, December.
  2. Michiel S. Heijden & Thomas Powles & Daniel Petrylak & Ronald Wit & Andrea Necchi & Cora N. Sternberg & Nobuaki Matsubara & Hiroyuki Nishiyama & Daniel Castellano & Syed A. Hussain & Aristotelis Bamia, 2022. "Predictive biomarkers for survival benefit with ramucirumab in urothelial cancer in the RANGE trial," Nature Communications, Nature, vol. 13(1), pages 1-15, December.
  3. Jodi M. Carter & Saranya Chumsri & Douglas A. Hinerfeld & Yaohua Ma & Xue Wang & David Zahrieh & David W. Hillman & Kathleen S. Tenner & Jennifer M. Kachergus & Heather Ann Brauer & Sarah E. Warren & , 2023. "Distinct spatial immune microlandscapes are independently associated with outcomes in triple-negative breast cancer," Nature Communications, Nature, vol. 14(1), pages 1-14, December.
  4. Yixuan Liu & Ying Xie & Yuling Chen & Jialun Duan & Chunjie Bao & Jinling Wang & Hexuan Feng & Mengjie Wang & Yuxin Ren & Peishan Li & Qian Luo & Jiarui Xu & Min Jiang & Yanchen Men & Yang Wu & Jianwe, 2025. "A protease-cleavable liposome for co-delivery of anti-PD-L1 and doxorubicin for colon cancer therapy in mice," Nature Communications, Nature, vol. 16(1), pages 1-22, December.
  5. Kristian Bjørn Hessellund & Ganggang Xu & Yongtao Guan & Rasmus Waagepetersen, 2022. "Second‐order semi‐parametric inference for multivariate log Gaussian Cox processes," Journal of the Royal Statistical Society Series C, Royal Statistical Society, vol. 71(1), pages 244-268, January.
  6. Rachael M. Zemek & Wee Loong Chin & Vanessa S. Fear & Ben Wylie & Thomas H. Casey & Cath Forbes & Caitlin M. Tilsed & Louis Boon & Belinda B. Guo & Anthony Bosco & Alistair R. R. Forrest & Michael J. , 2022. "Temporally restricted activation of IFNβ signaling underlies response to immune checkpoint therapy in mice," Nature Communications, Nature, vol. 13(1), pages 1-16, December.
  7. Stefanie Hiltbrunner & Lena Cords & Sabrina Kasser & Sandra N. Freiberger & Susanne Kreutzer & Nora C. Toussaint & Linda Grob & Isabelle Opitz & Michael Messerli & Martin Zoche & Alex Soltermann & Mar, 2023. "Acquired resistance to anti-PD1 therapy in patients with NSCLC associates with immunosuppressive T cell phenotype," Nature Communications, Nature, vol. 14(1), pages 1-14, December.
  8. Isaac Dean & Colin Y. C. Lee & Zewen K. Tuong & Zhi Li & Christopher A. Tibbitt & Claire Willis & Fabrina Gaspal & Bethany C. Kennedy & Veronika Matei-Rascu & Rémi Fiancette & Caroline Nordenvall & Ul, 2024. "Rapid functional impairment of natural killer cells following tumor entry limits anti-tumor immunity," Nature Communications, Nature, vol. 15(1), pages 1-18, December.
  9. Weicai Huang & Yuming Jiang & Wenjun Xiong & Zepang Sun & Chuanli Chen & Qingyu Yuan & Kangneng Zhou & Zhen Han & Hao Feng & Hao Chen & Xiaokun Liang & Shitong Yu & Yanfeng Hu & Jiang Yu & Yan Chen & , 2022. "Noninvasive imaging of the tumor immune microenvironment correlates with response to immunotherapy in gastric cancer," Nature Communications, Nature, vol. 13(1), pages 1-14, December.
  10. Yingying Shen & Chaojie Lu & Zhengbo Song & Chenxiao Qiao & Jiaoli Wang & Jinbiao Chen & Chengyan Zhang & Xianchang Zeng & Zeyu Ma & Tao Chen & Xu Li & Aifu Lin & Jufeng Guo & Jianli Wang & Zhijian Ca, 2022. "Ursodeoxycholic acid reduces antitumor immunosuppression by inducing CHIP-mediated TGF-β degradation," Nature Communications, Nature, vol. 13(1), pages 1-14, December.
  11. Kelsey B. Bennion & Danya Liu & Abdelhameed S. Dawood & Megan M. Wyatt & Katie L. Alexander & Mohamed S. Abdel-Hakeem & Chrystal M. Paulos & Mandy L. Ford, 2024. "CD8+ T cell-derived Fgl2 regulates immunity in a cell-autonomous manner via ligation of FcγRIIB," Nature Communications, Nature, vol. 15(1), pages 1-15, December.
  12. Elaine Lai-Han Leung & Run-Ze Li & Xing-Xing Fan & Lily Yan Wang & Yan Wang & Zebo Jiang & Jumin Huang & Hu-Dan Pan & Yue Fan & Hongmei Xu & Feng Wang & Haopeng Rui & Piu Wong & Hermi Sumatoh & Michae, 2023. "Longitudinal high-dimensional analysis identifies immune features associating with response to anti-PD-1 immunotherapy," Nature Communications, Nature, vol. 14(1), pages 1-9, December.
  13. Lin-Yu Yu & Jie Tang & Cong-Min Zhang & Wen-Jing Zeng & Han Yan & Mu-Peng Li & Xiao-Ping Chen, 2017. "New Immunotherapy Strategies in Breast Cancer," IJERPH, MDPI, vol. 14(1), pages 1-18, January.
  14. Yu-Ting Yen & May Chien & Pei-Yi Wu & Chi-Chang Ho & Chun-Te Ho & Kevin Chih-Yang Huang & Shu-Fen Chiang & K. S. Clifford Chao & William Tzu-Liang Chen & Shih-Chieh Hung, 2021. "Protein phosphatase 2A inactivation induces microsatellite instability, neoantigen production and immune response," Nature Communications, Nature, vol. 12(1), pages 1-14, December.
  15. Fengqiao Li & Xue-Qing Zhang & William Ho & Maoping Tang & Zhongyu Li & Lei Bu & Xiaoyang Xu, 2023. "mRNA lipid nanoparticle-mediated pyroptosis sensitizes immunologically cold tumors to checkpoint immunotherapy," Nature Communications, Nature, vol. 14(1), pages 1-16, December.
  16. Shiying Tang & Xiaofang Che & Jinyan Wang & Ce Li & Xin He & Kezuo Hou & Xiaojie Zhang & Jia Guo & Bowen Yang & Danni Li & Lili Cao & Xiujuan Qu & Zhenning Wang & Yunpeng Liu, 2025. "T-bet+CD8+ T cells govern anti-PD-1 responses in microsatellite-stable gastric cancers," Nature Communications, Nature, vol. 16(1), pages 1-17, December.
  17. Jingjie Yi & Omid Tavana & Huan Li & Donglai Wang & Richard J. Baer & Wei Gu, 2023. "Targeting USP2 regulation of VPRBP-mediated degradation of p53 and PD-L1 for cancer therapy," Nature Communications, Nature, vol. 14(1), pages 1-17, December.
  18. Su Yin Lim & Elena Shklovskaya & Jenny H. Lee & Bernadette Pedersen & Ashleigh Stewart & Zizhen Ming & Mal Irvine & Brindha Shivalingam & Robyn P. M. Saw & Alexander M. Menzies & Matteo S. Carlino & R, 2023. "The molecular and functional landscape of resistance to immune checkpoint blockade in melanoma," Nature Communications, Nature, vol. 14(1), pages 1-18, December.
  19. Yingtong Hou & Bo Lin & Tianyi Xu & Juan Jiang & Shuli Luo & Wanna Chen & Xinwen Chen & Yuanqi Wang & Guanrui Liao & Jianping Wang & Jiayuan Zhang & Xuyang Li & Xiao Xiang & Yubin Xie & Ji Wang & Sui , 2024. "The neurotransmitter calcitonin gene-related peptide shapes an immunosuppressive microenvironment in medullary thyroid cancer," Nature Communications, Nature, vol. 15(1), pages 1-19, December.
  20. Arta M. Monjazeb & Megan E. Daly & Guillaume Luxardi & Emanual Maverakis & Alexander A. Merleev & Alina I. Marusina & Alexander Borowsky & Amin Mirhadi & Stephen L. Shiao & Laurel Beckett & Shuai Chen, 2023. "Atezolizumab plus stereotactic ablative radiotherapy for medically inoperable patients with early-stage non-small cell lung cancer: a multi-institutional phase I trial," Nature Communications, Nature, vol. 14(1), pages 1-14, December.
  21. Clemens Hinterleitner & Jasmin Strähle & Elke Malenke & Martina Hinterleitner & Melanie Henning & Marco Seehawer & Tatjana Bilich & Jonas Heitmann & Martina Lutz & Sven Mattern & Sophia Scheuermann & , 2021. "Platelet PD-L1 reflects collective intratumoral PD-L1 expression and predicts immunotherapy response in non-small cell lung cancer," Nature Communications, Nature, vol. 12(1), pages 1-16, December.
  22. Le Qin & Yuanbin Cui & Tingjie Yuan & Dongmei Chen & Ruocong Zhao & Shanglin Li & Zhiwu Jiang & Qiting Wu & Youguo Long & Suna Wang & Zhaoyang Tang & Huixia Pan & Xiaoping Li & Wei Wei & Jie Yang & Xu, 2022. "Co-expression of a PD-L1-specific chimeric switch receptor augments the efficacy and persistence of CAR T cells via the CD70-CD27 axis," Nature Communications, Nature, vol. 13(1), pages 1-14, December.
  23. Jing Liu & Xia Bu & Chen Chu & Xiaoming Dai & John M. Asara & Piotr Sicinski & Gordon J. Freeman & Wenyi Wei, 2023. "PRMT1 mediated methylation of cGAS suppresses anti-tumor immunity," Nature Communications, Nature, vol. 14(1), pages 1-15, December.
  24. Lei Guan & Bin Wu & Ting Li & Lynn A. Beer & Gaurav Sharma & Mingyue Li & Chin Nien Lee & Shujing Liu & Changsong Yang & Lili Huang & Dennie T. Frederick & Genevieve M. Boland & Guangcan Shao & Tatyan, 2022. "HRS phosphorylation drives immunosuppressive exosome secretion and restricts CD8+ T-cell infiltration into tumors," Nature Communications, Nature, vol. 13(1), pages 1-12, December.
  25. Xinyu Bai & Grace H. Attrill & Tuba N. Gide & Peter M. Ferguson & Kazi J. Nahar & Ping Shang & Ismael A. Vergara & Umaimainthan Palendira & Ines Pires Silva & Matteo S. Carlino & Alexander M. Menzies , 2024. "Stroma-infiltrating T cell spatiotypes define immunotherapy outcomes in adolescent and young adult patients with melanoma," Nature Communications, Nature, vol. 15(1), pages 1-13, December.
  26. Yi Zhang & Mingjie Wang & Ling Ye & Shengqi Shen & Yuxi Zhang & Xiaoyu Qian & Tong Zhang & Mengqiu Yuan & Zijian Ye & Jin Cai & Xiang Meng & Shiqiao Qiu & Shengzhi Liu & Rui Liu & Weidong Jia & Xianzh, 2024. "HKDC1 promotes tumor immune evasion in hepatocellular carcinoma by coupling cytoskeleton to STAT1 activation and PD-L1 expression," Nature Communications, Nature, vol. 15(1), pages 1-14, December.
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