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Cost of Poor Adherence to Anti-Hypertensive Therapy in Europe


  • Francesco Saverio Mennini

    () (CEIS University of Rome "Tor Vergata")

  • Andrea Marcellusi

    () (CEIS University of Rome "Tor Vergata")

  • J.Matthias Graf von der Schulenburg

    () (Center for Health Economics Research Hannover(CHERH),Leibniz Universität Hannover)

  • Alastair Gray

    () (Health Economics Research Centre, Department of Public Health, University of Oxford)

  • Pierre L. Levy

    () (PSL-Université Paris-Dauphine)

  • Paolo Sciattella

    () (CEIS University of Rome “Tor Vergata”)

  • Marco Soro

    () (Market Access Dept. - Daiichi Sankyo Europe, Munich)

  • Gianandrea Staffiero

    () (Department of Economics and Business, CRES, Universitat Pompeu Fabra Barcelona)

  • Jan Zeidler

    () (Center for Health Economics Research Hannover(CHERH),Leibniz Universität Hannover)

  • Aldo Maggioni

    () (Associazione Nazionale Medici Cardiologi Ospedalieri Research Center, Florence)

  • Roland.E. Schmieder

    () (Department of Nephrology and Hypertension, University Hospital Erlangen)


Background: The financial burden for EU health systems associated with cardiovascular disease has been estimated to be nearly € 110 billion in 2006, corresponding to 10% of total healthcare expenditure across EU or a mean € 223 annual cost per capita. The main purpose of this study is to estimate the costs related to hypertension and the economic impact of increasing adherence to anti-hypertensive therapy in 5 European countries (Italy, Germany, France, Spain and England). Methods: A probabilistic prevalence-based decision tree model was developed to estimate the direct costs of cardiovascular disease related to hypertension (CV defined as: stroke, heart attack, kidney disease, heart failure) in 5 European countries. Our model considered adherence to hypertension treatment as a main driver of blood pressure control (BP

Suggested Citation

  • Francesco Saverio Mennini & Andrea Marcellusi & J.Matthias Graf von der Schulenburg & Alastair Gray & Pierre L. Levy & Paolo Sciattella & Marco Soro & Gianandrea Staffiero & Jan Zeidler & Aldo Maggion, 2013. "Cost of Poor Adherence to Anti-Hypertensive Therapy in Europe," CEIS Research Paper 299, Tor Vergata University, CEIS, revised 13 Dec 2013.
  • Handle: RePEc:rtv:ceisrp:299

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