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Economics of Switching from Vial to Disposable Pen Among Insulin Glargine-Treated Patients with Type 2 Diabetes Mellitus

Author

Listed:
  • Xie, Lin
  • Zhou, Steve
  • Wei, Wenhui
  • Gill, Jasvinder
  • Pan, Chunshen
  • Baser, Onur

Abstract

Objective: The study was designed to evaluate real-world data on clinical and economic outcome differences between patients with type 2 diabetes mellitus (T2DM) who use insulin glargine with vial-and-syringe delivery and those who switch to pen administration. Subjects and Methods: This retrospective study analyzed medical and pharmacy claims information from the national managed-care IMPACT® database (Ingenix Inc., Salt Lake City, UT). Adults with T2DM treated with insulin glargine were evaluated. Clinical and economic outcomes over 1 year were compared between individuals who had converted from administering glargine via vial-and-syringe to the SoloSTAR® (sanofi-aventis U.S., Bridgewater, NJ) pen (Switchers) and patients who continued to use vial-and-syringe administration (Continuers). Patients from each cohort were matched using propensity score matching for a comparison sample. Results: In total, 3,893 eligible patients were identified (665 Switchers and 3,228 Continuers), with a matched cohort with 603 patients in each group. Baseline characteristics were similar between groups. One-year treatment persistence was signifi-cantly higher with Switchers versus Continuers (65.3% vs. 49.8%; P

Suggested Citation

  • Xie, Lin & Zhou, Steve & Wei, Wenhui & Gill, Jasvinder & Pan, Chunshen & Baser, Onur, 2013. "Economics of Switching from Vial to Disposable Pen Among Insulin Glargine-Treated Patients with Type 2 Diabetes Mellitus," MPRA Paper 102739, University Library of Munich, Germany.
  • Handle: RePEc:pra:mprapa:102739
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    File URL: https://mpra.ub.uni-muenchen.de/102739/1/MPRA_paper_102739.pdf
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    More about this item

    Keywords

    Vial to Disposable Pen; Insulin Glargine-Treated Patients; Diabetes Mellitus;
    All these keywords.

    JEL classification:

    • C0 - Mathematical and Quantitative Methods - - General
    • I1 - Health, Education, and Welfare - - Health

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