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The Brain’s Innovation Engine: Locus Coeruleus’ Function in Creative Thinking and Foresight

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  • Roibu, Tib

Abstract

This paper explores the role of the locus coeruleus (LC) in driving innovation and adaptive thinking through its uncertainty-processing mechanisms. The research examines how this small brainstem nucleus orchestrates cognitive flexibility and creative problem-solving through targeted norepinephrine release. By understanding these neural mechanisms, a method is proposed—the Blue Spot Method—that systematically leverages LC-mediated cognitive processes through integrated cognitive modules, that work in harmony with the brain’s natural uncertainty-processing mechanisms.

Suggested Citation

  • Roibu, Tib, 2025. "The Brain’s Innovation Engine: Locus Coeruleus’ Function in Creative Thinking and Foresight," OSF Preprints e9xfc_v1, Center for Open Science.
    • Handle: RePEc:osf:osfxxx:e9xfc_v1
    DOI: 10.31219/osf.io/e9xfc_v1
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    References listed on IDEAS

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    1. Anna C Sales & Karl J Friston & Matthew W Jones & Anthony E Pickering & Rosalyn J Moran, 2019. "Locus Coeruleus tracking of prediction errors optimises cognitive flexibility: An Active Inference model," PLOS Computational Biology, Public Library of Science, vol. 15(1), pages 1-24, January.
    2. Tomonori Takeuchi & Adrian J. Duszkiewicz & Alex Sonneborn & Patrick A. Spooner & Miwako Yamasaki & Masahiko Watanabe & Caroline C. Smith & Guillén Fernández & Karl Deisseroth & Robert W. Greene & Ric, 2016. "Locus coeruleus and dopaminergic consolidation of everyday memory," Nature, Nature, vol. 537(7620), pages 357-362, September.
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