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Unlocking the broader value of biologic therapies through biosimilar-enabled access and repositioning

Author

Listed:
  • Mikel Berdud
  • Paul Oyalo
  • Libby Tungate
  • Lou Garrison
  • Amanda Cole

Abstract

Biologic medicines account for over 40% of global pharmaceutical spend. When originator patents expire, biosimilar competition should drive prices down, generating cost-savings, broadening access, and improving outcomes, yet that promise remains largely unrealised. From the first US launch in 2015 up to 2025, biosimilars saved the US health system an estimated $56.2 billion in drug costs, but one analysis estimates that $124.5 billion in savings could be achieved: a $68 billion gap. Supply- and demand-side barriers as well as contracting structures produce low penetration, recurring shortage risk, and a growing ‘biosimilar void’. The dominant policy response has been narrow, focusing…

Suggested Citation

  • Mikel Berdud & Paul Oyalo & Libby Tungate & Lou Garrison & Amanda Cole, 2026. "Unlocking the broader value of biologic therapies through biosimilar-enabled access and repositioning," Contract Research 002537, Office of Health Economics.
    • Handle: RePEc:ohe:conres:002537
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    JEL classification:

    • I1 - Health, Education, and Welfare - - Health

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