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On the equivalence of the net benefit and the Fieller's methods for statistical inference in cost-effectiveness analysis

Author

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  • Zethraeus, Niklas

    (Dept. of Economics, Stockholm School of Economics)

  • Löthgren, Mickael

    (AstraZeneca R&D Södertälje)

Abstract

This paper shows that there exists a close relation between the net benefit and Fieller's methods for calculation of confidence intervals and performing hypothesis testing in cost-effectiveness analysis. The prices at which the net benefit confidence interval limits are equal to zero are identical to the Fieller's confidence interval limits for the incremental cost-effectiveness ratio.

Suggested Citation

  • Zethraeus, Niklas & Löthgren, Mickael, 2000. "On the equivalence of the net benefit and the Fieller's methods for statistical inference in cost-effectiveness analysis," SSE/EFI Working Paper Series in Economics and Finance 379, Stockholm School of Economics.
  • Handle: RePEc:hhs:hastef:0379
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    Citations

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    Cited by:

    1. Niklas Zethraeus & Magnus Johannesson & Bengt Jönsson & Mickael Löthgren & Magnus Tambour, 2003. "Advantages of Using the Net-Benefit Approach for Analysing Uncertainty in Economic Evaluation Studies," PharmacoEconomics, Springer, vol. 21(1), pages 39-48, January.

    More about this item

    Keywords

    Confidence intervals; cost-effectiveness analysis; Fieller's method; hypothesis testing; net benefit;
    All these keywords.

    JEL classification:

    • D61 - Microeconomics - - Welfare Economics - - - Allocative Efficiency; Cost-Benefit Analysis
    • I10 - Health, Education, and Welfare - - Health - - - General
    • I12 - Health, Education, and Welfare - - Health - - - Health Behavior

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