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Patterns of Methylphenidate Use and Assessment of Its Abuse among the ă General Population and Individuals with Drug Dependence

Author

Listed:
  • Elisabeth Frauger
  • Despina Amaslidou
  • Michel Spadari
  • Veronique Allaria-Lapierre
  • David Braunstein
  • Vincent Sciortino
  • Xavier Thirion
  • Samira Djezzar
  • Joëlle Micallef

    (INT - Institut de Neurosciences de la Timone - AMU - Aix Marseille Université - CNRS - Centre National de la Recherche Scientifique)

Abstract

Purpose: The aim of this study was to describe the extent of ă methylphenidate (MPH) abuse and characterize its patterns by following ă several cases involving intravenous administration of crushed MPH ă tablets. Methods: First, a drug reimbursement database (covering 4 ă million inhabitants) was explored to assess the magnitude of MPH abuse ă among the general population, and second, a specific study based on ă individuals with drug dependence was performed to describe abusers' ă characteristics (n = 64), patterns of abuse and clinical implications. ă Results: From 2005 to 2011, the number of patients who were dispensed ă MPH at least once increased by 166%. The patients with `deviant' ă patterns of MPH consumption were mainly male adults with opiate ă maintenance treatment reimbursements. MPH abusers had precarious living ă conditions. Half of them consumed MPH daily by intravenous route and ă reported amphetamine-like effects (cardiovascular events, weight loss, ă psychiatric adverse events). Conclusion: Given the increase of MPH use, ă it is important to warn the scientific community about possible MPH ă abuse, especially in individuals with drug dependence. This study has ă facilitated public health intervention and dissemination of information ă related to MPH abuse among health care professionals at local and ă national levels. (C) 2015 S. Karger AG, Basel

Suggested Citation

  • Elisabeth Frauger & Despina Amaslidou & Michel Spadari & Veronique Allaria-Lapierre & David Braunstein & Vincent Sciortino & Xavier Thirion & Samira Djezzar & Joëlle Micallef, 2016. "Patterns of Methylphenidate Use and Assessment of Its Abuse among the ă General Population and Individuals with Drug Dependence," Post-Print hal-01482640, HAL.
    • Handle: RePEc:hal:journl:hal-01482640
    DOI: 10.1159/000439273
    as

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    Keywords

    Quality of Life;

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