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Treatment failure following excision therapy of CIN: the impact of ă direct colposcopic vision during procedure

Author

Listed:
  • Mellie Heineman
  • Julien Mancini

    (SESSTIM - U912 INSERM - Aix Marseille Univ - IRD - Sciences Economiques et Sociales de la Santé & Traitement de l'Information Médicale - IRD - Institut de Recherche pour le Développement - AMU - Aix Marseille Université - INSERM - Institut National de la Santé et de la Recherche Médicale, IPC - Institut Paoli-Calmettes - Fédération nationale des Centres de lutte contre le Cancer (FNCLCC), BiosTIC - Biostatistique et technologies de l'information et de la communication (BioSTIC) - [Hôpital de la Timone - APHM] - APHM - Assistance Publique - Hôpitaux de Marseille - TIMONE - Hôpital de la Timone [CHU - APHM])

  • Julia Villeret
  • Aubert Agostini
  • Gilles Houvenaeghel

    (IPC - Institut Paoli-Calmettes - Fédération nationale des Centres de lutte contre le Cancer (FNCLCC), Paoli Calmette - Département de chirurgie Paoli Calmette)

  • Leon Boubli

    (AMU MED - Aix-Marseille Université - Faculté de médecine - AMU - Aix Marseille Université)

  • Xavier Carcopino

    (Service de gynécologie-obstétrique [Hôpital Nord - APHM] - AMU - Aix Marseille Université - APHM - Assistance Publique - Hôpitaux de Marseille - Hôpital Nord [CHU - APHM], IMBE - Institut méditerranéen de biodiversité et d'écologie marine et continentale - AU - Avignon Université - AMU - Aix Marseille Université - Institut de recherche pour le développement [IRD] : UMR237 - CNRS - Centre National de la Recherche Scientifique)

Abstract

To assess whether the use of direct colposcopic vision during excision ă therapy of cervical intraepithelial neoplasia (CIN) has an impact on the ă risk of treatment failure. ă Data from 285 patients who had had excision therapy with proven CIN at ă specimen histological analysis were reviewed. Primary endpoint was the ă occurrence of post-treatment failure defined by the histological ă diagnosis of CIN 2-3 during follow-up. Data were analysed according to ă the use of colposcopy at the time of initial therapy of CIN. ă The use of direct colposcopic vision (DCV) resulted in a significant ă reduction in the mean height (p = 0.008) and diameter (p

Suggested Citation

  • Mellie Heineman & Julien Mancini & Julia Villeret & Aubert Agostini & Gilles Houvenaeghel & Leon Boubli & Xavier Carcopino, 2016. "Treatment failure following excision therapy of CIN: the impact of ă direct colposcopic vision during procedure," Post-Print hal-01482539, HAL.
  • Handle: RePEc:hal:journl:hal-01482539
    DOI: 10.1007/s00404-015-3887-7
    as

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