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Do pharmacist-led medication reviews in hospitals help reduce hospital readmissions? A systematic review and meta-analysis

Author

Listed:
  • Pierre Renaudin

    (TIMONE - Hôpital de la Timone [CHU - APHM])

  • Laurent Boyer

    (C3M - Centre méditerranéen de médecine moléculaire - UNS - Université Nice Sophia Antipolis (1965 - 2019) - INSERM - Institut National de la Santé et de la Recherche Médicale - UniCA - Université Côte d'Azur)

  • Marie-Anne Esteve

    (CRO2 - Centre de Recherches en Oncologie biologique et Oncopharmacologie - AMU - Aix Marseille Université - TIMONE - Hôpital de la Timone [CHU - APHM] - INSERM - Institut National de la Santé et de la Recherche Médicale, Service Pharmacie [Hôpital de la Timone - APHM] - AMU - Aix Marseille Université - APHM - Assistance Publique - Hôpitaux de Marseille - TIMONE - Hôpital de la Timone [CHU - APHM])

  • Pierre Bertault-Peres

    (Service Pharmacie [Hôpital de la Timone - APHM] - AMU - Aix Marseille Université - APHM - Assistance Publique - Hôpitaux de Marseille - TIMONE - Hôpital de la Timone [CHU - APHM])

  • Pascal Auquier

    (SPMC - Santé Publique et maladies Chroniques : Qualité de vie Concepts, Usages et Limites, Déterminants - AMU - Aix Marseille Université - APHM - Assistance Publique - Hôpitaux de Marseille)

  • Stéphane Honore

    (CRO2 - Centre de Recherches en Oncologie biologique et Oncopharmacologie - AMU - Aix Marseille Université - TIMONE - Hôpital de la Timone [CHU - APHM] - INSERM - Institut National de la Santé et de la Recherche Médicale, Service Pharmacie [Hôpital de la Timone - APHM] - AMU - Aix Marseille Université - APHM - Assistance Publique - Hôpitaux de Marseille - TIMONE - Hôpital de la Timone [CHU - APHM])

Abstract

AimsThe aim of this meta-analysis is to examine the impact of ă in-hospital pharmacist-led medication reviews in paediatric and adult ă patients. ă MethodsRelevant studies were identified from the Medline and Cochrane ă Library databases. Studies were included if they met the following ă criteria (without any language or date restrictions): design: randomized ă controlled trial; intervention: in-hospital pharmacist-led medication ă review (experimental group) vs. usual care (control group); ă participants: paediatric or adult population. The primary outcome was ă all-cause readmissions and/or emergency department (ED) visits at ă different time points. The secondary outcomes were all-cause ă readmissions, all-cause ED visits, drug-related readmissions, mortality, ă length of hospital stay, adherence and quality of life. We calculated ă the relative risk (RR) or mean differences (MD) with 95% confidence ă intervals (CIs) for each study. We used fixed and/or random effects ă models. Heterogeneity was assessed using the I-2 statistic. ă ResultsWe systematically reviewed 19 randomized controlled trials (4805 ă participants). The readmission rates did not differ between the ă experimental group and the control group (RR=0.97, 95% CI 0.89; 1.05, ă p=0.470). The secondary outcomes did not differ between the two groups, ă except for in drug-related readmissions, which were lower in the ă experimental group (RR=0.25, 95% CI 0.14; 0.45, p

Suggested Citation

  • Pierre Renaudin & Laurent Boyer & Marie-Anne Esteve & Pierre Bertault-Peres & Pascal Auquier & Stéphane Honore, 2016. "Do pharmacist-led medication reviews in hospitals help reduce hospital readmissions? A systematic review and meta-analysis," Post-Print hal-01482370, HAL.
    • Handle: RePEc:hal:journl:hal-01482370
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