IDEAS home Printed from https://ideas.repec.org/p/clt/sswopa/1066.html
   My bibliography  Save this paper

Statistical Analysis of the Additive and Multiplicative Hypotheses of Multiple Exposure Synergy For Cohort and Case-Control Studies

Author

Listed:
  • Dubin, Jeffrey A.

Abstract

This paper considers hypotheses tests for synergistic relationships in epidemiological studies. Two hypotheses are considered. First, I develop tests of the additive hypothesis which states that the combined risk from two sources of exposure is the sum of each risk taken separately. I then develop tests for the hypothesis that a multiplicative relationship exists for the risks, i.e., that the combined risk is consistent with the multiplication of the individual risks. Following standard practice in epidemiological studies I consider tests for both case-referent and cohort (standardized mortality rate) type studies.

Suggested Citation

  • Dubin, Jeffrey A., 1999. "Statistical Analysis of the Additive and Multiplicative Hypotheses of Multiple Exposure Synergy For Cohort and Case-Control Studies," Working Papers 1066, California Institute of Technology, Division of the Humanities and Social Sciences.
    • Handle: RePEc:clt:sswopa:1066
    as

    Download full text from publisher

    File URL: http://www.hss.caltech.edu/SSPapers/wp1066.pdf
    Download Restriction: no
    ---><---

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:clt:sswopa:1066. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Victoria Mason (email available below). General contact details of provider: http://www.hss.caltech.edu/ss .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.