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Application of a LIMS in a pharmaceutical drug metabolism and pharmacokinetics laboratory

In: Advanced LIMS Technology

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  • D. J. M. Graham

Abstract

One of the initial major impacts of mainstream commercial Laboratory Information Management Systems (LIMS) has been on conventional chemistry laboratories which analyse samples from some form of process chemistry against a specification, followed by production of a certificate of analysis based on the results of that analysis and subsequent approval of that sample for further use [1]. In such cases, the analysis of a given sample is generally independent of the analysis of other samples being analysed at the same time. This meant that the LIMS databases were very much sample- and specification-orientated, and little or no functionality was provided to allow the manipulation of batches of related samples. In time, as the acceptance of these applications has become fact, some vendors have made attempts to increase the market appeal of their systems by attempting to promote a broader applicability without changing the basic underlying structure of their systems. They have done this by adding functionalities to support this wider applicability of their system.

Suggested Citation

  • D. J. M. Graham, 1995. "Application of a LIMS in a pharmaceutical drug metabolism and pharmacokinetics laboratory," Springer Books, in: J. E. H. Stafford (ed.), Advanced LIMS Technology, chapter 4, pages 54-70, Springer.
  • Handle: RePEc:spr:sprchp:978-94-011-0615-3_4
    DOI: 10.1007/978-94-011-0615-3_4
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