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Numerical Investigation of the Micromechanical Behavior of DNA Immersed in a Hydrodynamic Flow

In: High Performance Computing in Science and Engineering, Garching/Munich 2009

Author

Listed:
  • Sergey Litvinov

    (Technische Universität München, Lehrstuhl für Aerodynamik)

  • Marco Ellero

    (Technische Universität München, Lehrstuhl für Aerodynamik)

  • Xiangyu Hu

    (Technische Universität München, Lehrstuhl für Aerodynamik)

  • Nikolaus Adams

    (Technische Universität München, Lehrstuhl für Aerodynamik)

Abstract

The topic of the project is relevant to the development of novel single-molecule manipulation techniques in biophysics and bionanotechnology where complex DNA-liquid interactions occur. The goals of the project are to verify the proposed numerical method by comparing the results for simple flow conditions with available numerical and analytical results, to analyze the dynamics of the DNA macromolecular exposed to an uniform and shear flow, perform simulations corresponding to the more complex experimental conditions.

Suggested Citation

  • Sergey Litvinov & Marco Ellero & Xiangyu Hu & Nikolaus Adams, 2010. "Numerical Investigation of the Micromechanical Behavior of DNA Immersed in a Hydrodynamic Flow," Springer Books, in: Siegfried Wagner & Matthias Steinmetz & Arndt Bode & Markus Michael Müller (ed.), High Performance Computing in Science and Engineering, Garching/Munich 2009, pages 147-160, Springer.
    • Handle: RePEc:spr:sprchp:978-3-642-13872-0_13
    DOI: 10.1007/978-3-642-13872-0_13
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