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Traffic of Molecular Motors: From Theory to Experiments

In: Traffic and Granular Flow ’07

Author

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  • Paolo Pierobon

    (Institut Curie, CNRS UMR 168)

Abstract

Summary Intracellular transport along microtubules or actin filaments, powered by molecular motors such as kinesins, dyneins or myosins, has been recently modeled using one-dimensional driven lattice gases. We discuss some generalizations of these models, that include extended particles and defects. We investigate the feasibility of single molecule experiments aiming to measure the average motor density and to locate the position of traffic jams by mean of a tracer particle. Finally, we comment on preliminary single molecule experiments performed in living cells.

Suggested Citation

  • Paolo Pierobon, 2009. "Traffic of Molecular Motors: From Theory to Experiments," Springer Books, in: Cécile Appert-Rolland & François Chevoir & Philippe Gondret & Sylvain Lassarre & Jean-Patrick Lebacq (ed.), Traffic and Granular Flow ’07, pages 679-688, Springer.
    • Handle: RePEc:spr:sprchp:978-3-540-77074-9_76
    DOI: 10.1007/978-3-540-77074-9_76
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