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Assessment of Health Related Quality of Life

In: Fundamentals of Clinical Trials

Author

Listed:
  • Lawrence M. Friedman
  • Curt D. Furberg

    (Wake Forest School of Medicine, Division of Public Health Sciences)

  • David L. DeMets

    (University of Wisconsin, Department Biostatistics and Medical Informatics)

  • David M. Reboussin

    (Wake Forest School of Medicine, Department of Biostatistics)

  • Christopher B. Granger

    (Duke University, Department of Medicine)

  • Michelle J. Naughton

    (The Ohio State University)

  • Sally A. Shumaker

    (Wake Forest School of Medicine)

Abstract

The major goal of randomized clinical trials is to determine the potential benefits and harms of an intervention. The benefits of most available interventions in medicine are symptom improvements. Thus, relief or reduction of symptoms is a common primary outcome in clinical trials (Chap. 3 ). Most of the adverse effects of interventions are also symptom-related (Chap. 12 ). Any changes in symptomatology are subjective and reported by trial participants. A special form of participant reported outcomes relate to various types of functioning, traditionally covered by the term health-related quality of life (HRQL) [1–4].

Suggested Citation

  • Lawrence M. Friedman & Curt D. Furberg & David L. DeMets & David M. Reboussin & Christopher B. Granger & Michelle J. Naughton & Sally A. Shumaker, 2015. "Assessment of Health Related Quality of Life," Springer Books, in: Fundamentals of Clinical Trials, edition 0, chapter 0, pages 279-295, Springer.
    • Handle: RePEc:spr:sprchp:978-3-319-18539-2_13
    DOI: 10.1007/978-3-319-18539-2_13
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