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Fiber, a Software for Classification and Counting in Histological Images

In: Handbook of Visual, Experimental and Computational Mathematics

Author

Listed:
  • Erika Elizabeth Rodriguez-Torres

    (Autonomous University of Hidalgo State (UAEH), Academic Area of Mathematics and Physics)

  • Gonzalo Chávez-Fragoso

    (National Polytechnic Institute, Department of Computer Science, Center for Research and Advanced Studies)

  • Enrique Vázquez-Mendoza

    (National Polytechnic Institute, Department of Physiology, Biophysics and Neuroscience, Center for Research and Advanced Studies)

  • Cindy Xilonen Hinojosa-Rodríguez

    (National Polytechnic Institute, Department of Physiology, Biophysics and Neuroscience, Center for Research and Advanced Studies)

  • Kenia López-García

    (Department of Chemical and Biological Sciences, University of the Americas Puebla)

  • Jorge Viveros-Rogel

    (Autonomous University of Hidalgo State (UAEH), Academic Area of Mathematics and Physics)

  • Ismael Jiménez-Estrada

    (National Polytechnic Institute, Department of Physiology, Biophysics and Neuroscience, Center for Research and Advanced Studies)

Abstract

Histochemical staining techniques are used to identify and classify cell phenotypes, such as skeletal muscle fibers. Currently, the identification and classification of muscle fibers are performed by an expert through visual inspection of histological images. This type of classification requires a considerable investment of time and resources. In order to overcome this obstacle, this software was developed, Fiber, which allows the automation of the classification of muscle fibers in a short time and with high efficiency. Fiber is implemented in Java, which guarantees multi-platform support, and uses artificial intelligenceArtificial intelligence data mining algorithms for pattern recognition, such as K-meansK-means, fuzzy c-meansFuzzy c-means, and Kohonen self-organized mapsKohonen self-organized maps. An expert-supervised method is also included in the software to complement the algorithms. The spreadsheet data can later be used to study the distribution patterns and organization of muscle fibers under both normal and pathological conditions. The results of the various analyses performed by the software are not only highly accurate, but the processing time is reduced by up to 90% compared to the processing time without the software. Expert assistance improves the performance of the software.

Suggested Citation

  • Erika Elizabeth Rodriguez-Torres & Gonzalo Chávez-Fragoso & Enrique Vázquez-Mendoza & Cindy Xilonen Hinojosa-Rodríguez & Kenia López-García & Jorge Viveros-Rogel & Ismael Jiménez-Estrada, 2026. "Fiber, a Software for Classification and Counting in Histological Images," Springer Books, in: Bharath Sriraman (ed.), Handbook of Visual, Experimental and Computational Mathematics, pages 77-107, Springer.
  • Handle: RePEc:spr:sprchp:978-3-032-16368-4_6
    DOI: 10.1007/978-3-032-16368-4_6
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