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Spatiotemporal Dynamics of Fractional Hepatitis B Virus Infection Model with Humoral and Cellular Immunity

In: Trends in Biomathematics: Chaos and Control in Epidemics, Ecosystems, and Cells

Author

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  • Moussa Bachraoui

    (Hassan II University, Laboratory of Analysis, Modeling and Simulation (LAMS), Faculty of Science Ben M’sik)

  • Khalid Hattaf

    (Hassan II University, Laboratory of Analysis, Modeling and Simulation (LAMS), Faculty of Science Ben M’sik
    Centre Régional des Métiers de l’Education et de la Formation (CRMEF))

  • Noura Yousfi

    (Hassan II University, Laboratory of Analysis, Modeling and Simulation (LAMS), Faculty of Science Ben M’sik)

Abstract

In this chapter, we propose a mathematical model governed by fractional partial differential equations (FPDEs) that describes the dynamics of hepatitis B virus (HBV) infection in presence of humoral and cellular immune responses which are mediated by antibodies and cytotoxic T lymphocytes (CTL) cells. The incidence of infection is modeled by Hattaf-Yousfi functional response that includes various forms existing in the literature. Furthermore, the global properties of the model are rigorously investigated. Finally, numerical simulations are presented to support the analytical results.

Suggested Citation

  • Moussa Bachraoui & Khalid Hattaf & Noura Yousfi, 2021. "Spatiotemporal Dynamics of Fractional Hepatitis B Virus Infection Model with Humoral and Cellular Immunity," Springer Books, in: Rubem P. Mondaini (ed.), Trends in Biomathematics: Chaos and Control in Epidemics, Ecosystems, and Cells, pages 293-313, Springer.
  • Handle: RePEc:spr:sprchp:978-3-030-73241-7_19
    DOI: 10.1007/978-3-030-73241-7_19
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