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Physiological and Inflammatory Activity in Various Conditions

In: Understanding Fever and Body Temperature

Author

Listed:
  • Ewa Grodzinsky

    (Linköping University)

  • Märta Sund Levander

    (Linköping University)

Abstract

The adaptive immune response is a critical component of the host’s defence and is essential for maintaining health. Hypersensitivity is usually classified into four immunological mechanisms, Type I–IV. Autoimmune diseases are pathological processes directed against the host’s own tissues, either organ-specific or systemic reactions. The process is a chronic activation of the immune system in which the innate system activates the adaptive system and causes inflammation. Autoinflammatory diseases are syndromes, also called periodic fever syndromes, which occur in the absence of infection. The process is chronic activation of the immune system and more often periodic than progressive. Immunodeficiencies occur when one or more components of the immune system are defective. It is innate or adaptive depending on which component of the immune system is defective. The relationship between immunodeficiency and autoimmune diseases is well established, for example, malignancies, endocrine disorders, atherosclerosis, inflammation, and pain.

Suggested Citation

  • Ewa Grodzinsky & Märta Sund Levander, 2020. "Physiological and Inflammatory Activity in Various Conditions," Springer Books, in: Ewa Grodzinsky & Märta Sund Levander (ed.), Understanding Fever and Body Temperature, chapter 0, pages 115-127, Springer.
    • Handle: RePEc:spr:sprchp:978-3-030-21886-7_8
    DOI: 10.1007/978-3-030-21886-7_8
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