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Analysis of Pharmacokinetic Data

In: Applied Statistics in the Pharmaceutical Industry

Author

Listed:
  • Ha Nguyen

    (Merck Research Laboratories)

  • Dhammika Amaratunga

    (The R. W. Johnson Pharmaceutical Research Institute)

Abstract

Pharmacokinetics is the study of the time course of a drug administered to a biological organism, in particular, a human. A drug, following administration, is processed by the body in a series of stages: absorption, distribution, metabolism and elimination; these stages are often abbreviated by their initials, ADME. Since the nature, intensity, and duration of a drug’s biologic effects depend on the amount of drug available to the body and, more specifically, to the amount of drug available at the target site in the body, pharmacokinetic studies play an integral role in a drug’s development.

Suggested Citation

  • Ha Nguyen & Dhammika Amaratunga, 2001. "Analysis of Pharmacokinetic Data," Springer Books, in: Steven P. Millard & Andreas Krause (ed.), Applied Statistics in the Pharmaceutical Industry, chapter 5, pages 109-133, Springer.
    • Handle: RePEc:spr:sprchp:978-1-4757-3466-9_5
    DOI: 10.1007/978-1-4757-3466-9_5
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