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The 2MA Cell Cycle Model

In: Stochastic Approaches for Systems Biology

Author

Listed:
  • Mukhtar Ullah

    (University of Rostock, Department of Systems Biology and Bioinformatics Institute of Computer Science)

  • Olaf Wolkenhauer

    (University of Rostock, Department of Systems Biology and Bioinformatics Institute of Computer Science)

Abstract

In this chapter we take the Tyson–Novák model [108] for the fission yeast cell cycle as a case study [159]. This deterministic model is a practical example using nonelementary reactions and relative concentrations, the two central features of our extended 2MA approach. This will allow us to investigate the price of higher-order truncations by comparing the simulated cycle time statistics with experiments.

Suggested Citation

  • Mukhtar Ullah & Olaf Wolkenhauer, 2011. "The 2MA Cell Cycle Model," Springer Books, in: Stochastic Approaches for Systems Biology, chapter 0, pages 201-219, Springer.
    • Handle: RePEc:spr:sprchp:978-1-4614-0478-1_7
    DOI: 10.1007/978-1-4614-0478-1_7
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