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Neuromuscular Alterations of Upper Airway Muscles in Patients with OSAS: Radiological and Histopathological Findings

In: Data Mining for Biomarker Discovery

Author

Listed:
  • Panagis Drakatos

    (University Hospital of Patras)

  • Dimosthenis Lykouras

    (University Hospital of Patras)

  • Fotis Sampsonas

    (University Hospital of Patras)

  • Kiriakos Karkoulias

    (University Hospital of Patras)

  • Kostas Spiropoulos

    (University Hospital of Patras)

Abstract

This article reviews studies of upper airway muscles in humans, observed in patients with obstructive sleep apnea syndrome (OSAS). These studies include neuromuscular abnormalities of the upper airway muscles, along with changes of the upper airway lumen which is narrower in patients with OSAS than normal subjects. Several approaches have been made in the imaging of the upper airway using X-ray, CT, and MRI in order to characterize the severity of OSAS. Up to date results on histopathology of the muscles across with nervous lesions, are also reviewed.

Suggested Citation

  • Panagis Drakatos & Dimosthenis Lykouras & Fotis Sampsonas & Kiriakos Karkoulias & Kostas Spiropoulos, 2012. "Neuromuscular Alterations of Upper Airway Muscles in Patients with OSAS: Radiological and Histopathological Findings," Springer Optimization and Its Applications, in: Panos M. Pardalos & Petros Xanthopoulos & Michalis Zervakis (ed.), Data Mining for Biomarker Discovery, edition 127, chapter 0, pages 213-226, Springer.
    • Handle: RePEc:spr:spochp:978-1-4614-2107-8_12
    DOI: 10.1007/978-1-4614-2107-8_12
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