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An Exposure–Response Threshold for Lung Diseases Caused by Crystalline Silica

In: Improving Risk Analysis

Author

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  • Louis Anthony Cox

    (Cox Associates)

Abstract

This chapter further develops the concept of dose–response thresholds for exposure-related lung diseases, using crystalline silica as an example. It also discusses epidemiological evidence as well as biological evidence. For the sake of practitioners who may care more about such specific applications than about the more general theoretical framework of the preceding two chapters, this chapter is self-contained; it briefly summarizes the relevant biology and the alternative basins-of-attraction modeling framework as they apply specifically to crystalline silica.

Suggested Citation

  • Louis Anthony Cox, 2012. "An Exposure–Response Threshold for Lung Diseases Caused by Crystalline Silica," International Series in Operations Research & Management Science, in: Improving Risk Analysis, edition 127, chapter 0, pages 311-335, Springer.
  • Handle: RePEc:spr:isochp:978-1-4614-6058-9_11
    DOI: 10.1007/978-1-4614-6058-9_11
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