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Role of Heavy Metals in the Incidence of Human Cancers

In: Heavy Metals - Their Environmental Impacts and Mitigation

Author

Listed:
  • Vincent Salvatore Gallicchio
  • Juley Harper

Abstract

There has been increased concern on many levels focused on the environmental and occupational exposure of heavy metals and their impact on disease, specifically the carcinogenic potential inducing cancer in humans. Because the impact of heavy metals on human health continues to be a major health concern, research continues to improve our understanding of the carcinogenic potential of these substances. Of particular concern have been human exposure to aluminum, arsenic, beryllium, cadmium, lead, mercury, nickel, and radium and their carcinogenic potential whether contact is via environmental or occupational exposure. This updated review focuses on the carcinogenic mechanisms heavy metals use to induce malignant transformation of cells as well as addressing the overall environmental and occupational hazards of heavy metal exposure.

Suggested Citation

  • Vincent Salvatore Gallicchio & Juley Harper, 2021. "Role of Heavy Metals in the Incidence of Human Cancers," Chapters, in: Mazen Nazal & Hongbo Zhao (ed.), Heavy Metals - Their Environmental Impacts and Mitigation, IntechOpen.
    • Handle: RePEc:ito:pchaps:219659
    DOI: 10.5772/intechopen.98259
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    File URL: https://www.intechopen.com/chapters/76911
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    More about this item

    Keywords

    heavy metals; carcinogenesis; human exposure; toxicity; mechanisms; remediation;
    All these keywords.

    JEL classification:

    • Q55 - Agricultural and Natural Resource Economics; Environmental and Ecological Economics - - Environmental Economics - - - Environmental Economics: Technological Innovation

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