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NSTAGEBIN: Stata module to provide facilities for optimising and designing multi-arm multi-stage (MAMS) randomised controlled trials with binary outcomes

Author

Listed:
  • Babak Choodari-Oskooei

    (MRC Clinical Trials Unit at UCL, London, UK)

  • Daniel J. Bratton

    (Clinical Statistics, GlaxoSmithKline, Stevenage, UK)

  • Mahesh KB Parmar

    (MRC Clinical Trials Unit at UCL, London, UK)

Programming Language

Stata

Abstract

nstagebin specifies the design (sample size, duration and overall pairwise operating characteristics) of a multi-arm, multi-stage (MAMS) trial using a binary intermediate (I) outcome at the interim stages and a binary definitive (D) outcome at the final stage, both analysed using an absolute difference in proportions. See Bratton, Phillips & Parmar (2013) for a description of the design and Royston, Barthel, Parmar, Oskooei & Isham (2011) for a description of a similar MAMS design for time-to-event outcomes.

Suggested Citation

  • Babak Choodari-Oskooei & Daniel J. Bratton & Mahesh KB Parmar, 2023. "NSTAGEBIN: Stata module to provide facilities for optimising and designing multi-arm multi-stage (MAMS) randomised controlled trials with binary outcomes," Statistical Software Components S459248, Boston College Department of Economics.
    • Handle: RePEc:boc:bocode:s459248
    Note: This module should be installed from within Stata by typing "ssc install nstagebin". The module is made available under terms of the MIT license (https://opensource.org/licenses/MIT).
    as

    Download full text from publisher

    File URL: http://fmwww.bc.edu/repec/bocode/n/nstagebin.ado
    File Function: program code
    Download Restriction: no
    File URL: http://fmwww.bc.edu/repec/bocode/n/nstagebinopt.ado
    File Function: program code
    Download Restriction: no
    File URL: http://fmwww.bc.edu/repec/bocode/n/nstagebin.dlg
    File Function: program code
    Download Restriction: no
    File URL: http://fmwww.bc.edu/repec/bocode/n/nstagebin.sthlp
    File Function: help file
    Download Restriction: no
    File URL: http://fmwww.bc.edu/repec/bocode/n/nstagebinopt.sthlp
    File Function: help file
    Download Restriction: no
    File URL: http://fmwww.bc.edu/repec/bocode/n/nstagebin_example.do
    File Function: sample do-file
    Download Restriction: no
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