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IPDPOWER: Stata module to perform simulation based power calculations for mixed effects modelling

Author

Listed:
  • Evangelos Kontopantelis

    (Faculty of Medicine, University of Manchester)

Programming Language

Stata

Abstract

ipdpower is a simulations-based command that calculates power for complex mixed effects two-level data structures. The command was developed having individual patient data meta-analyses in mind, where patients are nested within studies, but the methods apply to any two-level structure (say patients within general practices in a primary care database). The command proceeds in two steps. First, it generates the outcome data according to the specified coefficients for the intercept, the exposure (intervention), the covariate and the exposure-covariate interaction and the outcome can be continuous, binary or count data (selected using outc(#). Second, it uses regression modelling (selected using model(#) to return average model fit statistics, power and coverage calculations. Power indicates the percentage of iterations in which a model coefficient was found to be statistically significant and of the same direction as the hypothesised. Coverage indicates the percentage of confidence intervals that include the true coefficient and should correspond to the hypothesised alpha level. Binomial confidence intervals using the cii command are calculated for both power and coverage.

Suggested Citation

  • Evangelos Kontopantelis, 2015. "IPDPOWER: Stata module to perform simulation based power calculations for mixed effects modelling," Statistical Software Components S457959, Boston College Department of Economics, revised 08 Nov 2018.
    • Handle: RePEc:boc:bocode:s457959
    Note: This module should be installed from within Stata by typing "ssc install ipdpower". The module is made available under terms of the GPL v3 (https://www.gnu.org/licenses/gpl-3.0.txt). Windows users should not attempt to download these files with a web browser.
    as

    Download full text from publisher

    File URL: http://fmwww.bc.edu/repec/bocode/i/ipdpower.ado
    File Function: program code
    Download Restriction: no
    File URL: http://fmwww.bc.edu/repec/bocode/i/ipdpower.sthlp
    File Function: help file
    Download Restriction: no
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