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BCII: Stata module to to estimate the number needed to treat (NNT) and confidence intervals for patients improving, or ‘benefiting’ (either improvements gained or deteriorations prevented), in a randomised controlled trial

Author

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  • Robert Froud

    () (Queen Mary, University of London)

Abstract

Estimation of absolute risk reduction and number needed to treat for the difference between the proportion of improving patients in an intervention group and the proportion of improving patients a control group of a clinical trial. The package uses a method that is considered to have superior coverage properties to the conventional Wald method for calculating confidence intervals (Newcombe's Method 10); this may be important when reciprocally transforming absolute risk reductions to obtain numbers needed to treat (NNTs) as described by Bender, 2001. The program also estimates NNTs for benefit; the difference between the proportion of improving patients minus the proportion of deteriorating patients in the intervention group and the proportion of improving patients minus the proportion of deteriorating patients in the control group. Newcombe’s method 10 has been modified to incorporate these extra variance terms as described by Froud et al, 2009.

Suggested Citation

  • Robert Froud, 2009. "BCII: Stata module to to estimate the number needed to treat (NNT) and confidence intervals for patients improving, or ‘benefiting’ (either improvements gained or deteriorations prevented), in a rando," Statistical Software Components S457053, Boston College Department of Economics.
  • Handle: RePEc:boc:bocode:s457053
    Note: This module should be installed from within Stata by typing "ssc install bcii". Windows users should not attempt to download these files with a web browser.
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    File URL: http://fmwww.bc.edu/repec/bocode/b/bcii.ado
    File Function: program code
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    File URL: http://fmwww.bc.edu/repec/bocode/b/bcii.sthlp
    File Function: help file
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    File URL: http://fmwww.bc.edu/repec/bocode/b/bcib.ado
    File Function: program code
    Download Restriction: no

    File URL: http://fmwww.bc.edu/repec/bocode/b/bcib.sthlp
    File Function: help file
    Download Restriction: no

    More about this item

    Keywords

    number needed to treat; NNT; Wilson scores;

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