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Reducing the Burden of Mental Illness in Spain: Population-Level Impact and Cost-Effectiveness of Treatments in Depression and Schizophrenia

  • Ayuso-Mateos José Luis



  • Gutiérrez Recacha Pedro
  • Maria Haro Josep



  • Salvador Carulla Luis


  • Vázquez Polo Francisco José


  • Negrín Hernández Miguel Angel


  • Chisholm Daniel


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    The present study aims to estimate the cost-effectiveness of interventions for reducing the burden of depression and schizophrenia in Spain and evaluate their population level impact. The study examines the cost-effectiveness of different types of clinical interventions at the level of the Spanish population. For depression, the interventions considered are the following: 1) tricyclic antidepressants (imipramine); 2) SSRIs (fluoxetine); 3) psychotherapy; 4) tricyclic antidepressants plus psychotherapy; 5) SSRIs plus psychotherapy; 6) proactive collaboration management with tricyclic antidepressants; and 7) proactive collaboration management with SSRIs. In our analysis, interventions based on tricyclic antidepressants turned out to be the most cost-efficient option. For schizophrenia, the interventions considered are the following: 1) current situation; 2) older antipsychotics alone; 3) new antipsychotics alone (risperidone); 4) older antipsychotics plus psychosocial treatment; 5) new antipsychotics plus psychosocial treatment; 6) older antipsychotics plus case management and psychosocial treatment; and 7) new antipsychotics plus case management and psychosocial treatment. Interventions based on the combination of old antipsychotics with psychosocial treatment or psychosocial treatment plus case management proved to be the most efficient strategies according to our analysis. Provider_Name: Fundacion BBVA / BBVA Foundation

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    This book is provided by Fundacion BBVA / BBVA Foundation in its series Reports with number 20119 and published in 2008.
    ISBN: 978-84-96515-69-7
    Handle: RePEc:fbb:report:20119
    Contact details of provider: Postal: Plaza de San Nicolás, 4, 48005 Bilbao
    Phone: +34 94 487 52 52
    Fax: +34 94 424 46 21
    Web page:

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