Bridelia Ferruginea Bark: Phytochemical Analysis And Bioactivity Assessment For Potential Therapeutic Applications

Bridelia ferruguinea bark is investigated for its phytochemical composition and bioactivity to explore its therapeutic potential. The phytochemical analysis reveals significant quantities of alkaloids (62.95 mg/g), saponins (64.31 mg/g), flavonoids (100.19 mg/g), tannins (78.08 mg/g), and phenols (253.62 mg/g). The nitrogen-free extract dominates at 53.23%, followed by crude fiber at 24.44%. Additionally, the moisture, crude protein, crude fat, and ash content in Bridelia ferruguinea bark powder are reported at 7.63%, 2.15%, 8.72%, and 3.83%, respectively. Assessment of bioactivity indicates a lipid inhibition percentage of 23.88% and a vitamin C content of 55.97%. Moreover, the bark exhibits Fe chelation (13.44%) and DPPH radical scavenging activity (83.54%). Furthermore, it demonstrates inhibition of albumin denaturation (62.71%) and antiproteinase activity (69.534%). Importantly, it shows promising α-amylase inhibition (37.60%) and α-glucosidase inhibition (58.07%). These diverse bioactivities suggest potential applications in pharmaceuticals and nutraceuticals, warranting further studies for formulation development targeting both human and animal health. Bridelia ferruguinea bark emerges as a valuable natural resource with multifaceted therapeutic prospects, inviting extensive exploration for practical utilization.